PLoS Computational Biology is a peer-reviewed computational biology journal established in 2005 and published by the nonprofit Public Library of Science in association with the International Society for Computational Biology. Its Editor in Chief is Philip Bourne. All articles are open access and licensed under the Creative Commons Attribution License. The journal is well-known beyond its core field for its Ten Simple Rules series of articles that capture the essence of selected aspects of research in computational biology or in science more generally, e.g. how to present a poster, how to collaborate, or how to edit Wikipedia. Due to their free licensing, files from PLoS Computational Biology can be reused in places other than the journal s website, e.g. to illustrate Wikipedia articles.
A new computational framework has revealed key differences between four rheumatoid arthritis medications and their impact on biological pathways in mice. Niki Karagianni of Biomedcode Hellas SA, Greece, and colleagues present ...
May 09, 2019
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Human perception is based on mathematically optimal principles, but the brain implements those principles imperfectly, suggests new research by Elina Stengård and Ronald van den Berg of the University of Uppsala, Sweden. ...
Apr 18, 2019
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Psychology researchers who have hypothesized that we classify scenery by following some order of cognitive priorities may have been overlooking something simpler. New evidence suggests that the fastest categorizations our ...
Sep 03, 2015
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Cancer cells may rely on opportunism, as well as chemical signalling, to spread through the body, according to new findings by mathematicians at the University of Birmingham.
May 02, 2019
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We may cave in to peer pressure, marketing and persuasion, but faced with decisions, the default response programmed into our brains is to say "no", a recent study suggests.
May 27, 2015
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It is estimated that each year in the United States 2 million people become infected with bacteria that are resistant to one or more types of antibiotics, and at least 23,000 people will die because of these infections. This ...
Oct 09, 2015
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In a collaborative study led by Sanford Burnham Prebys Medical Discovery Institute (SBP), researchers have combined two publicly available 'omics' databases to create a new catalogue of 'cancer drivers'. Cancer drivers are ...
Oct 20, 2015
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The hippocampus plays a crucial role in memory formation. However, it is not yet fully understood in what way that brain structure's individual regions are involved in the formation of memories. Neuroscientists at the Collaborative ...
Jun 03, 2015
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Influenza pandemics are potentially the most serious natural catastrophes that affect the human population. New findings published in PLOS Computational Biology suggest that with both timely and accurate data and sophisticated ...
Sep 24, 2015
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Researchers funded by the National Institutes of Health Genotype-Tissue Expression (GTEx) project have created a new and much-anticipated data resource to help establish how differences in an individual's genomic make-up ...
May 07, 2015
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