Proceedings of the National Academy of Sciences

Medications

A new drug candidate can shrink kidney cysts

Autosomal dominant polycystic kidney disease (ADPKD), the most common form of polycystic kidney disease, can lead to kidney enlargement and eventual loss of function. The disease affects more than 12 million people worldwide, ...

Immunology

A new targeted treatment calms the cytokine storm

Cytokines are chemical messengers that help the body get rid of invading bacteria and viruses, and control inflammation. The body carefully balances cytokines because they help keep the immune system healthy. However, this ...

Immunology

Nasal spray with antibodies could prevent COVID-19

Researchers at Karolinska Institutet have shown that nasal drops with IgA antibodies can protect mice from SARS-CoV-2 infection. The results imply a new way to protect individuals at high risk from different variants of the ...

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