Science Immunology

Oncology & Cancer

Cancer immunotherapy uses melanin against melanoma

Researchers have developed a melanin-enhanced cancer immunotherapy technique that can also serve as a vaccine, based on early experiments done in a mouse model. The technique is applied via a transdermal patch.

Immunology

How do MAIT cells identify and attack foreign invaders?

Melbourne researchers have identified what makes a specialised immune cell, known as mucosal-associated invariant T (MAIT), cells boost their numbers and attack foreign invaders at the site of the infection.

Medical research

Scientists find timekeepers of gut's immune system

As people go through their daily and nightly routines, their digestive tracts follow a routine, too: digesting food and absorbing nutrients during waking hours, and replenishing worn-out cells during sleep. Shift work and ...

Oncology & Cancer

Inactive receptor renders cancer immunotherapies ineffective

The aim of immunotherapies is to enable the immune system to fight cancer on its own. Drugs known as checkpoint inhibitors are already in clinical use for this purpose. However, they are only effective in about one-third ...

Immunology

How the immune system's key organ regenerates itself

With advances in cancer immunotherapy splashing across headlines, the immune system's powerful cancer assassins—T cells—have become dinner-table conversation. But hiding in plain sight behind that "T" is the organ from ...

Oncology & Cancer

Immunity against melanoma is only skin deep

In a newly published study, researchers at Dartmouth's Norris Cotton Cancer Center find that unique immune cells, called resident memory T cells, do an outstanding job of preventing melanoma. The work began with the question ...

Immunology

New vaccine prevents herpes in mice, guinea pigs

Researchers from the Perelman School of Medicine at the University of Pennsylvania have developed a vaccine to protect against genital herpes. Tested on both mice and guinea pigs, the immunization led to "mostly sterilizing ...

Oncology & Cancer

Antibody for fighting cancer emerges

While studying the underpinnings of multiple sclerosis, investigators at Brigham and Women's Hospital came across important clues for how to treat a very different disease: cancer. In a paper published in Science Immunology, ...

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