When pathogens invade or tumor cells emerge, the immune system is alerted by danger signals that summon a key battalion of first responders, the unsung heroes of the immune system—a population of starfish-shaped sentinels ...
Canadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components interacts with the cell membrane.
The human heart works under high demand, constantly pumping oxygen-rich blood through the body. When faced with disease, however, fulfilling this demand can become increasingly difficult and harmful. In the case of chronic ...
Mar 30, 2021
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Researchers from the Institute of Glycomics have identified a novel bacterial sensor in Campylobacter species that enable the pathogenic cells to find suitable host cells. The findings have been published in Science Signalling.
In the early days of the COVID-19 pandemic, it was established that SARS-CoV-2 infects cells by binding to the human protein ACE2, which plays a role in regulating blood pressure. But ACE2 is almost absent in human lung cells, ...
Feb 11, 2021
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The molecular details of how SARS-CoV-2 enters cells and infects them are still not clear. Researchers at Uppsala University have tested the bioinformatic predictions made by another research group and have identified receptors ...
Feb 8, 2021
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A team of neuroscientists has identified a potential means to address the loss of cognitive function due to Alzheimer's disease by targeting protein synthesis in mice. Their findings, reported in the journal Science Signaling, ...
Feb 2, 2021
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A naturally occurring antibody capable of stimulating the body's immune-suppressing regulatory T cells has been discovered by a team of Harvard scientists, a finding that may eventually open a new door into kinder, gentler ...
One of the many wonders—and mysteries—of human biology is the complex response of the innate immune system, which is known for its swiftness in annihilating invading pathogens and capacity to mount an explosive inflammatory ...
A University of Ottawa study has found a specific Alzheimer's treatment is effective in male and not female mice, providing a window into the biology of the disease and the effectiveness of targeted treatments.
Dec 21, 2020
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