Stem Cells and Development is globally recognized as the trusted source for critical, even controversial coverage of emerging hypotheses and novel findings. With a focus on stem cells of all tissue types and their potential therapeutic applications, the Journal provides clinical, basic, and translational scientists with cutting-edge research and findings.
Challenging the U.S. Food and Drug Administration's current approach to evaluating and approving adipose-based cell therapies used in reparative medicine, a group of researchers proposes a new path forward that focuses on ...
Feb 19, 2020
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Researchers have reported for the first time producing feline induced pluripotent stem cells (fiPSCs) from adult cells of domestic cats. The methods and implications of this research are published in Stem Cells and Development.
Oct 17, 2019
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Although the literature describes the mammalian zygote as a totipotent cell, one researcher challenges this view and has proposed a revised alternative model of mammalian cellular totipotency. The basis for this new model ...
Aug 19, 2019
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Researchers have developed a guide to help labs standardize the production of mature hepatic-like cells (HPCs) from stem cells and easily compare gene expression of HPCs to actual human liver tissue. This moderately high ...
Aug 14, 2019
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A new review of data from 12 spaceflight experiments and simulated microgravity studies has shown that microgravity does not have a negative effect on stem-like cell-dependent tissue regeneration in newts, but in some tissues ...
Mar 25, 2019
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Researchers report the identification of a novel transcription factor that helps regulate the differentiation of mesenchymal stem cells (MSCs) into bone in mice. Bone cell differentiation is still poorly understood, and MSCs ...
Mar 11, 2019
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Researchers used time-lapse imaging to show that mouse induced pluripotent stem cells (iPSCs) grown during spaceflight differentiated into cardiomyocytes significantly faster than similar cells grown at Earth's gravity. The ...
Mar 06, 2019
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A new study takes a close look at the content and potential implications of the new Texas law HB 810, which aims to expand assess of experimental stem cell interventions outside the realm of clinical trials under FDA oversight. ...
Oct 30, 2018
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Researchers have performed a careful comparison between locally generated, ischemia-induced, multipotent stem cells (iSCs) and bone marrow-derived mesenchymal stem cells (BM-MSCs) in an effort to determine which cell type ...
Oct 27, 2018
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Researchers have made a significant new discovery concerning the signaling mechanisms that enable newts to regrow their tails after injury. Specifically, this process is shown to require the coordinated activation of the ...
Sep 20, 2018
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