Structure is a peer-reviewed scientific journal founded by Wayne A. Hendrickson, Carl-Ivar Brändén and Alan R. Fersht in September 1993. It focuses on protein structure and related issues. The journal is published monthly by Cell Press. The current editors are Christopher D. Lima and Andrej Sali.
The elucidation of the role of a critical protein in cell biology is paving the way for alternative cancer treatments. By refuting recent challenges that threatened to invalidate their work, a team of KAUST researchers investigating ...
Aug 24, 2023
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Researchers at Sanford Burnham Prebys, collaborating with scientists from Eli Lilly and Company, have revealed the structure and function of a drug called LY3361237, which can reduce the harmful activity of the immune system ...
Jun 5, 2023
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Parkinson's disease is the second most common neurodegenerative disease and affects more than 10 million people around the world. To better understand the origins of the disease, researchers from Penn State College of Medicine ...
May 19, 2021
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Experiments led by researchers at the Department of Energy's Oak Ridge National Laboratory have determined that several hepatitis C drugs can inhibit the SARS-CoV-2 main protease, a crucial protein enzyme that enables the ...
Nov 16, 2020
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What causes neurons to die in Parkinson's disease? Parkinson's disease is a long-term (chronic) neurological condition that affects around 12,000 people in Ireland and between 7 and 10 million people worldwide.
Feb 13, 2020
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A discovery in a protein associated with glaucoma was so unheard of that for over two years, researchers ran it through a gauntlet of lab tests and published a new research paper on it. The tests validated what they initially ...
Oct 20, 2017
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In the quest to understand the driving forces behind neurodegenerative diseases, researchers in recent years have zeroed in on clumps of malfunctioning proteins thought to kill neurons in the brain and spinal cord by jamming ...
Sep 22, 2016
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In amyotrophic lateral sclerosis, aggregates of the protein TDP-43 are almost always found in afflicted neurons and glial cells. Meanwhile, about 50 ALS-linked mutations are known to affect a particular region of TDP-43. ...
Aug 18, 2016
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(Medical Xpress)—New insights into a protein complex that regulates the very tips of chromosomes could improve methods of screening anti-cancer drugs.
Nov 29, 2012
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Scientists from the Florida campus of The Scripps Research Institute (TSRI) have defined the molecular structure of an enzyme as it interacts with several proteins involved in outcomes that can influence neurodegenerative ...
Nov 8, 2012
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