ranslational Oncology publishes the results of novel research investigations which bridge the laboratory and clinical settings including risk assessment, cellular and molecular characterization, prevention, detection, diagnosis and treatment of human cancers with the overall goal of improving the clinical care of oncology patients. Translational Oncology will publish laboratory studies of novel therapeutic interventions as well as clinical trials which evaluate new treatment paradigms for cancer. Peer reviewed manuscript types include Original Reports, Reviews, Editorials and Brief Articles.
Versions of an antibiotic drug called DON first isolated from soil bacteria more than 60 years ago have shown promising signs of extending survival in mice models of especially lethal pediatric brain tumors marked by the ...
Sep 23, 2019
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The environment in which breast cancer arises—the interplay between the patient's BMI, tumor size and cancer-specific proteins—is of importance for the prognosis. This is shown in a study from Lund University in Sweden. ...
Aug 25, 2022
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Oral malignancies represent the seventh-most common cancer worldwide. Many diagnosed patients relapse, despite radical resection of the primary oral squamous cell carcinoma (OSCC) lesion. Therefore, understanding the local ...
Oct 25, 2021
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Long-term cognitive problems are a frequent side effect in children undergoing life-saving radiation therapy for medulloblastoma—the most common malignant pediatric brain tumor. Medulloblastoma affects between 250 and 500 ...
Jul 10, 2019
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Patients diagnosed with pancreatic cancer face a poor prognosis because the tumor forms dense scar-like tissue that is difficult for chemotherapy drugs to penetrate, but a new model may help researchers develop new therapies.
Dec 4, 2018
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Cancer is one of the major causes of death worldwide affecting 8.2 million of people per year, and in the US, the number of new cases will achieve 1.6 million in 2017. The global impact of this disease costs a trillion of ...
Aug 28, 2017
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Investigators at the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute are developing a novel, multistep investigational treatment for one of the most complex and difficult-to-treat forms of the disease, locally advanced ...
Jul 22, 2014
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A drug developed at Linköping University in Sweden protects against the side effects of cancer treatments while strengthening the effects on the tumour. An international drug evaluation is now starting up on a larger group ...
Jan 22, 2013
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According to a new research, circulating tumor DNA can be used detect treatment options for ovarian cancer patients who don't benefit from chemotherapy.
May 7, 2019
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