DegraSense Ltd: Commercial sense and sensor abilities

October 14, 2008,

A new company, DegraSense Ltd, has been established to develop a point of care dental diagnostic that could improve the treatment of periodontal disease and other inflammatory conditions.

The new Queen Mary spin out aims to commercialise novel protease biosensor technology developed from the research activities of Dr Steffi Krause from the School of Engineering and Materials Science, and Dr Mike Watkinson from the School of Biological and Chemical Sciences.

Drs Krause and Watkinson believe there are potential applications for the biosensor technology in a range of industries including environmental and food testing, but they will initially focus on developing a non-invasive sensor capable of monitoring inflammation and bacterial infection. The initial application will be the diagnosis and treatment of periodontal disease, estimated to cost the NHS £250 million per year.

There are currently no accurate clinical methods for dentists to distinguish between active and dormant sites in periodontal disease progression. DegraSense plans to develop a low cost, disposable biosensor that will enable a dentist to identify areas of active inflammation immediately prior to treatment. This will enable more efficient targeting of expensive and labour intensive surgical treatment for patients with gum disease.

Dr Krause, who has been appointed founder Director of the new company said: "This is a new and exciting prospect. It brings together a number of years of research and the involvement of industrial partners so we can push forward towards a product that can make a real difference to dental treatment everywhere. The diagnosis of periodontal disease should reduce the incidences of invasive and uncomfortable dental procedures to the patient and at the same time should bring significant savings both to the patient and the health care provider."

Source: Queen Mary, University of London

Explore further: Systematic treatment of periodontal disease: Advantage of further therapeutic approaches

Related Stories

Systematic treatment of periodontal disease: Advantage of further therapeutic approaches

April 30, 2018
The German Institute for Quality and Efficiency in Health Care (IQWiG) investigated the advantages and disadvantages of different treatments of inflammatory disease of the periodontium. The final report is now available. ...

Researchers discover cellular messengers communicate with bacteria in the mouth

May 8, 2018
A new UCLA-led study provides clear evidence that cellular messengers in saliva may be able to regulate the growth of oral bacteria responsible for diseases, such as periodontitis and meningitis.

People with diabetes visit the dentist less frequently despite link between diabetes, oral health

April 2, 2018
Adults with diabetes are less likely to visit the dentist than people with prediabetes or without diabetes, finds a new study led by researchers at NYU Rory Meyers College of Nursing and East Carolina University's Brody School ...

Primary care physicians report feeling unprepared for role in prenatal oral health

March 19, 2018
A new study from the University of North Carolina at Chapel Hill suggests that primary care physicians may feel underequipped to provide adequate oral health counseling to pregnant women. Poor maternal oral health can have ...

Good oral hygiene may help recovery after a heart attack

April 20, 2018
Good oral hygiene may help recovery after acute cardiovascular events such as heart attacks and aortic dissection, according to research presented today at Frontiers in CardioVascular Biology (FCVB) 2018, a European Society ...

Study reveals new link between periodontal and cerebrovascular diseases

July 18, 2016
A new study has revealed a relationship between chronic periodontitis and lacunar infarct, two common diseases in the elderly. Chronic periodontitis is an inflammatory disease of the gums, whereas lacunar infarct is a type ...

Recommended for you

Best of Last Year—The top Medical Xpress articles of 2017

December 20, 2017
It was a good year for medical research as a team at the German center for Neurodegenerative Diseases, Magdeburg, found that dancing can reverse the signs of aging in the brain. Any exercise helps, the team found, but dancing ...

Pickled in 'cognac', Chopin's heart gives up its secrets

November 26, 2017
The heart of Frederic Chopin, among the world's most cherished musical virtuosos, may finally have given up the cause of his untimely death.

Sugar industry withheld evidence of sucrose's health effects nearly 50 years ago

November 21, 2017
A U.S. sugar industry trade group appears to have pulled the plug on a study that was producing animal evidence linking sucrose to disease nearly 50 years ago, researchers argue in a paper publishing on November 21 in the ...

Female researchers pay more attention to sex and gender in medicine

November 7, 2017
When women participate in a medical research paper, that research is more likely to take into account the differences between the way men and women react to diseases and treatments, according to a new study by Stanford researchers.

Drug therapy from lethal bacteria could reduce kidney transplant rejection

August 3, 2017
An experimental treatment derived from a potentially deadly microorganism may provide lifesaving help for kidney transplant patients, according to an international study led by investigators at Cedars-Sinai.

Exploring the potential of human echolocation

June 25, 2017
People who are visually impaired will often use a cane to feel out their surroundings. With training and practice, people can learn to use the pitch, loudness and timbre of echoes from the cane or other sounds to navigate ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.