DegraSense Ltd: Commercial sense and sensor abilities

October 14, 2008,

A new company, DegraSense Ltd, has been established to develop a point of care dental diagnostic that could improve the treatment of periodontal disease and other inflammatory conditions.

The new Queen Mary spin out aims to commercialise novel protease biosensor technology developed from the research activities of Dr Steffi Krause from the School of Engineering and Materials Science, and Dr Mike Watkinson from the School of Biological and Chemical Sciences.

Drs Krause and Watkinson believe there are potential applications for the biosensor technology in a range of industries including environmental and food testing, but they will initially focus on developing a non-invasive sensor capable of monitoring inflammation and bacterial infection. The initial application will be the diagnosis and treatment of periodontal disease, estimated to cost the NHS £250 million per year.

There are currently no accurate clinical methods for dentists to distinguish between active and dormant sites in periodontal disease progression. DegraSense plans to develop a low cost, disposable biosensor that will enable a dentist to identify areas of active inflammation immediately prior to treatment. This will enable more efficient targeting of expensive and labour intensive surgical treatment for patients with gum disease.

Dr Krause, who has been appointed founder Director of the new company said: "This is a new and exciting prospect. It brings together a number of years of research and the involvement of industrial partners so we can push forward towards a product that can make a real difference to dental treatment everywhere. The diagnosis of periodontal disease should reduce the incidences of invasive and uncomfortable dental procedures to the patient and at the same time should bring significant savings both to the patient and the health care provider."

Source: Queen Mary, University of London

Explore further: Periodontal disease bacteria may kick-start Alzheimer's

Related Stories

Periodontal disease bacteria may kick-start Alzheimer's

October 4, 2018
Long-term exposure to periodontal disease bacteria causes inflammation and degeneration of brain neurons in mice that is similar to the effects of Alzheimer's disease in humans, according to a new study from researchers at ...

Low levels of vitamin D3 and periodontitis may trigger the onset of Type 2 diabetes

August 20, 2018
In a rare study of its kind, new University of Toronto research has identified how vitamin D3 and periodontitis influence Type 2 diabetes.

Gum disease treatment may improve symptoms in cirrhosis patients

August 29, 2018
Routine oral care to treat gum disease (periodontitis) may play a role in reducing inflammation and toxins in the blood (endotoxemia) and improving cognitive function in people with liver cirrhosis. The study is published ...

Aortic atherosclerotic plaque inflammation may contribute to the progression of fatty liver disease to liver fibrosis

August 2, 2018
The world's rising obesity epidemic is associated with a broad spectrum of ailments including atherosclerosis and non-alcoholic fatty liver (NAFL) disease. Each condition can progress from small fatty deposits to localized ...

Systematic treatment of periodontal disease: Advantage of further therapeutic approaches

April 30, 2018
The German Institute for Quality and Efficiency in Health Care (IQWiG) investigated the advantages and disadvantages of different treatments of inflammatory disease of the periodontium. The final report is now available. ...

Study reveals new link between periodontal and cerebrovascular diseases

July 18, 2016
A new study has revealed a relationship between chronic periodontitis and lacunar infarct, two common diseases in the elderly. Chronic periodontitis is an inflammatory disease of the gums, whereas lacunar infarct is a type ...

Recommended for you

Tongue-in-cheek Nobels honor nutritional analysis of cannibalism, roller-coaster kidney stones treatment

September 14, 2018
A nutritional analysis of cannibalism and treating kidney stones on roller-coasters were research projects honored by tongue-in-cheek awards at Harvard University Thursday, designed to make you laugh first, and think later.

Pediatric robot patient offers new level of realism for doctors in training

September 10, 2018
A team of researchers and engineers at Gaumard Scientific has unveiled a new robot that raises the bar on medical training devices. The robot, called HAL, has been made to look like a five-year-old male patient and offers ...

Why men say they've had more lifetime sexual partners than women

July 25, 2018
The disparity between the number of sexual partners reported by men and women can largely be explained by a tendency among men to report extreme numbers of partners, and to estimate rather than count their lifetime total, ...

Censors jump into action as China's latest vaccine scandal ignites

July 22, 2018
Chinese censors on Sunday deleted articles and postings about the vaccine industry as an online outcry over the country's latest vaccine scandal intensified.

Revenge of a forgotten medical 'genius'

June 30, 2018
It's not an uncommon fate for a pioneering scientist: languishing unrecognised in his time before dying in obscurity. But as his 200th birthday approaches, the life-saving work of a Hungarian obstetrician is finally getting ...

Yes, you can put too much chlorine in a pool

June 2, 2018
(HealthDay)—Before you take a dip in the pool this summer, be sure there's not too much chlorine in the water.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.