Journal retracts diabetes study published in 2000

April 1, 2009

(AP) -- A scientific journal is retracting a research paper published more than eight years ago that reported a gene therapy treatment had led to remission of Type 1 diabetes in rats and mice.

In its Thursday issue, Nature said the lead author of the paper - Hyun Chul Lee of Yonsei University in Seoul, South Korea - and two other authors asked for the retraction because they could not reproduce the experiment's results.

Another author maintains the results are still valid and did not join in the retraction request, the journal said. A fifth author is deceased.

In Type 1, or juvenile, , the body mistakenly attacks insulin-producing . Patients must inject themselves with to survive. The researchers reported eliminating the disease in rodents by slipping into them a man-made gene designed to produce an insulin-like chemical.

The authors wrote at the time that the approach might be useful for humans. But diabetes experts told The Associated Press in November 2000 that it wasn't clear the treatment would work in people.

---

On the Net:

Nature: http://www.nature.com/nature

©2009 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Related Stories

Recommended for you

Fabric imbued with optical fibers helps fight skin diseases

February 23, 2018
A team of researchers with Texinov Medical Textiles in France has announced that their PHOS-ISTOS system, called the Fluxmedicare, is on track to be made commercially available later this year. The system consists of a piece ...

DNA gets away: Scientists catch the rogue molecule that can trigger autoimmunity

February 22, 2018
A research team has discovered the process - and filmed the actual moment - that can change the body's response to a dying cell. Importantly, what they call the 'Great Escape' moment may one day prove to be the crucial trigger ...

Therapy for muscular dystrophy-caused heart failure also improves muscle function in mice

February 22, 2018
Injections of cardiac progenitor cells help reverse the fatal heart disease caused by Duchenne muscular dystrophy and also lead to improved limb strength and movement ability, a new study shows.

Low-calorie diet enhances intestinal regeneration after injury

February 22, 2018
Dramatic calorie restriction, diets reduced by 40 percent of a normal calorie total, have long been known to extend health span, the duration of disease-free aging, in animal studies, and even to extend life span in most ...

Gut microbes protect against sepsis—mouse study

February 22, 2018
Sepsis occurs when the body's response to the spread of bacteria or toxins to the bloodstream damages tissues and organs. The fight against sepsis could get a helping hand from a surprising source: gut bacteria. Researchers ...

Artificial intelligence quickly and accurately diagnoses eye diseases and pneumonia

February 22, 2018
Using artificial intelligence and machine learning techniques, researchers at Shiley Eye Institute at UC San Diego Health and University of California San Diego School of Medicine, with colleagues in China, Germany and Texas, ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.