A group of German investigators has published a randomized controlled trial on how to overcome constant worries in the current issue of Psyhotherapy and Psychosomatics.

Worry exposure (WE) is a core element of cognitive-behavioral treatment for generalized disorder (GAD). Its efficacy as a stand-alone treatment method (without further cognitive-behavioral therapy interventions) has never been tested. This study examined whether WE alone is as efficacious as the empirically supported stand-alone treatment for GAD, applied relaxation (AR).

In a randomized controlled study, 73 outpatients meeting DSM-IV criteria for GAD as primary diagnosis were allocated to either WE or AR or a waiting list control group; in a 2nd randomization procedure the waiting list subjects were reallocated to WE or AR. The treatment was manualized (15 sessions with WE or AR), included 6-month and 1-year follow-ups, as well as last observation carried forward and completer analyses, and was controlled for allegiance effects.The Hamilton Anxiety Rating Scale and the State-Trait Anxiety Scale were used as primary outcome measures. Self-report scales of anxiety, worrying and depression including negative metacognition about worrying and thought suppression served as secondary outcome measures.

The dropout rate was moderate. The pre-/posttreatment effects were high for the Hamilton Anxiety Rating Scale (standardized mean difference >1) and for the State-Trait Anxiety Inventory (standardized mean difference >0.87). The proportion of patients reaching high end state functioning was 48% (WE) and 56% (AR). WE and AR did not differ with regard to dropout rate or treatment effects. The treatment effects were stable at 6 month and 1 year follow-up.

This is the first study to show that a stand-alone exposure in sensu technique - WE - is efficacious in the treatment of GAD. Both AR and WE seem to represent effective principles of change in GAD.

More information: Hoyer, J.; Beesdo, K.; Gloster, A.T.; Runge, J.; Höfler, M.; Becker, E.S. Worry Exposure versus Applied Relaxation in the Treatment of Generalized Anxiety Disorder. Psychother Psychosom 2009;78:106-115.

Provided by Journal of Psychotherapy and Psychosomatics