Preventing HIV transmission during breastfeeding

October 20, 2010, University of Cambridge
Preventing HIV transmission during breastfeeding

In order to reduce the transmission of HIV from mother to baby during breastfeeding, scientists are developing a low-cost, modified nipple shield which dispenses antiviral compounds.

The novel research is highlighted in the following film.

Scientists at the University of Cambridge, with collaborators from the United States, are modifying a conventional nipple shield to include replaceable inserts. These inserts will contain an anti-viral agent which will be delivered to the infant while breastfeeding to prevent from an + mother.

They are currently exploring a number of cheap, edible microbicides which are deposited on the insert and released into the milk during breastfeeding, significantly reducing the HIV infectivity in the .

Breastfeeding accounts for up to one third of all mother-to-child transmissions of HIV, approximately 200,000 babies every year, primarily in Sub-Saharan Africa. Unfortunately, the mothers often have no alternative but to breastfeed as formula is typically even more deadly for the infant than the risk of HIV infection (due to the malnutrition and it often causes when used in low resource settings).

Stephen Gerrard, a PhD candidate at the Department of Chemical Engineering and Biotechnology at the University of Cambridge, stated: "The nipple shield could also deliver anti-retroviral drugs (ARVs) to non-infected infants - infant ARV prophylaxes (medicines given to prevent disease) is recommended by the if there is no acceptable, feasible, affordable, sustainable and safe alternative to breastfeeding for an HIV+ mother to her infant.

"This may also be an easier method of delivery than using oral syrup syringes, the current advised method of administration, and provide a new route for the delivery of many infant medications and nutritional supplements."

More information: The 'JustMilk' project stemmed from the International Design Development Summit 2008, for more information visit hpp://justmilk.org .

Related Stories

Recommended for you

War in Ukraine has escalated HIV spread in the country: study

January 15, 2018
Conflict in Ukraine has increased the risk of HIV outbreaks throughout the country as displaced HIV-infected people move from war-affected regions to areas with higher risk of transmission, according to analysis by scientists.

Researchers offer new model for uncovering true HIV mortality rates in Zambia

January 12, 2018
A new study that seeks to better ascertain HIV mortality rates in Zambia could provide a model for improved national and regional surveillance approaches, and ultimately, more effective HIV treatment strategies.

New drug capsule may allow weekly HIV treatment

January 9, 2018
Researchers at MIT and Brigham and Women's Hospital have developed a capsule that can deliver a week's worth of HIV drugs in a single dose. This advance could make it much easier for patients to adhere to the strict schedule ...

New long-acting, less-toxic HIV drug suppresses virus in humanized mice

January 8, 2018
A team of Yale researchers tested a new chemical compound that suppresses HIV, protects immune cells, and remains effective for weeks with a single dose. In animal experiments, the compound proved to be a promising new candidate ...

Usage remains low for pill that can prevent HIV infection

January 8, 2018
From gritty neighborhoods in New York and Los Angeles to clinics in Kenya and Brazil, health workers are trying to popularize a pill that has proven highly effective in preventing HIV but which—in their view—remains woefully ...

Researchers find clues to AIDS resistance in sooty mangabey genome

January 3, 2018
Peaceful co-existence, rather than war: that's how sooty mangabeys, a monkey species found in West Africa, handle infection by SIV, a relative of HIV, and avoid developing AIDS-like disease.

1 comment

Adjust slider to filter visible comments by rank

Display comments: newest first

junkd
not rated yet Nov 28, 2010
Reliable supplier, rapid delivery, guarantee!
http://star-of-he..._id=5831

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.