Incomplete recovery of lumbar discs two years after bed rest

June 22, 2012
Incomplete recovery of lumbar discs two years after bed rest
Recovery of the lumbar intervertebral discs following a 60-day period of bed rest is a lengthy process, with recovery incomplete at two years, according to a study published in the June 15 issue of Spine.

(HealthDay) -- Recovery of the lumbar intervertebral discs following a 60-day period of bed rest is a lengthy process, with recovery incomplete at two years, according to a study published in the June 15 issue of Spine.

Daniel L. Belavý, B.Phty., Ph.D., from the Charité Universitätsmedizin Berlin, and colleagues conducted a prospective longitudinal study to evaluate the recovery of the lumbar after bed rest. As part of the second Berlin BedRest Study, 24 male participants completed 60 days of head down tilt bed rest. Of these, 22 underwent magnetic resonance imaging at 180 days and 21 at two years after bed rest.

The researchers found that increases in disc volume and height and intervertebral length persisted at 180 days (P ≤ 0.0004) and 720 days (P ≤ 0.024) after bed rest, compared with prior to bed rest. At 180 days the disc signal intensity remained increased (P = 0.034), but at two years it was decreased compared with baseline (P = 0.018).

"The current study shows that the of the morphology of the lumbar intervertebral discs after prolonged is incomplete after two years," the authors write. "Further work is required to examine whether these persistent effects could be associated with increased disc injury risk."

The second Berlin BedRest Study was partially funded by the pharmaceutical and medical device industries.

Explore further: Exercise produces positive effects on the intervertebral discs

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Exercise produces positive effects on the intervertebral discs

June 28, 2011
Physical exercise has a positive effect on the formation of cells in the intervertebral discs. This is shown by a study from the Sahlgrenska Academy, University of Gothenburg, presented at the annual meeting of the International ...

Recommended for you

New test differentiates between Lyme disease, similar illness

August 16, 2017
Lyme disease is the most commonly reported vector-borne illness in the United States. But it can be confused with similar conditions, including Southern Tick-Associated Rash Illness. A team of researchers led by Colorado ...

Addressing superbug resistance with phage therapy

August 16, 2017
International research involving a Monash biologist shows that bacteriophage therapy – a process whereby bacterial viruses attack and destroy specific strains of bacteria - can be used successfully to treat systemic, multidrug ...

Can previous exposure to west Nile alter the course of Zika?

August 15, 2017
West Nile virus is no stranger to the U.S.-Mexico border; thousands of people in the region have contracted the mosquito-borne virus in the past. But could this previous exposure affect how intensely Zika sickens someone ...

Compounds in desert creosote bush could treat giardia and 'brain-eating' amoeba infections

August 15, 2017
Researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego and the University of Colorado Anschutz Medical Campus have found that compounds produced by the creosote bush, a ...

New malaria analysis method reveals disease severity in minutes

August 11, 2017
Left untreated, malaria can progress from being mild to severe—and potentially fatal—in 24 hours. So researchers at the University of British Columbia developed a method to quickly and sensitively assess the progression ...

Drug trial shows promise for deadly neurological disorder

August 10, 2017
Results of a small clinical trial show promise for treating a rare neurodegenerative condition that typically kills those afflicted before they reach age 20. The disease, called Niemann-Pick type C (NPC), causes cholesterol ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.