InteguSeal does not reduce scoliosis surgery infections

July 26, 2012
InteguSeal does not reduce scoliosis surgery infections
Preoperative cyanoacrylate sealant (InteguSeal) application does not reduce the risk of surgical site infection for patients undergoing scoliosis surgery, according to a study published online July 18 in Spine.

(HealthDay) -- Preoperative cyanoacrylate sealant (InteguSeal) application does not reduce the risk of surgical site infection for patients undergoing scoliosis surgery, according to a study published online July 18 in Spine.

Eric Dromzee, M.D., from the Université Pierre et Marie Curie in Paris, and colleagues randomly assigned 56 patients with neuromuscular or adolescent idiopathic scoliosis (AIS) to receive either a sterile, film-forming cyanoacrylate liquid application (InteguSeal) or no application. Infection occurrence was compared in the two groups.

The researchers found that the neuromuscular patients had more fused levels, increased intraoperative bleeding, and longer intraoperative time than AIS patients. Three deep and three superficial early postoperative infections of the posterior approach occurred in six patients. Five of the six infections occurred in patients treated with InteguSeal, but non-parametric statistical tests (Fischer exact test) showed no significant correlation (P = 0.096) between early postoperative infection occurrence and the use of InteguSeal. After local wound debridement and treatment with antibiotics all six cases had favorable outcomes.

"If microbial sealant may thus be a useful addition to a multimodal approach to minimize surgical site infection, there is currently insufficient evidence as to whether the use of microbial sealants reduces the risk of surgical site infection in people undergoing scoliosis surgery," the authors conclude.

Explore further: Lowest fused vertebral level linked to motion in scoliosis

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Lowest fused vertebral level linked to motion in scoliosis

May 10, 2012

(HealthDay) -- For postoperative patients with adolescent idiopathic scoliosis (AIS), preservation of vertebral motion segments allows for greater distribution of functional motion, according to a study published in the May ...

Instrumented spinal fusion method impacts infection rate

May 21, 2012

(HealthDay) -- For patients who undergo instrumented spinal fusion, the rates of infection are higher among those who receive posterior lumbar interbody fusion compared with those who receive posterior or posterolateral fusion, ...

Recommended for you

New trial for prosthetic hip joint infection

June 14, 2017

The first ever randomised trial to investigate why some patients develop infections after their hip or knee replacement surgery, and which type of surgical revision treatment is best is being run by the University of Bristol ...

Making prosthetic limbs feel more natural

May 31, 2017

A new surgical technique devised by MIT researchers could allow prosthetic limbs to feel much more like natural limbs. Through coordination of the patient's prosthetic limb, existing nerves, and muscle grafts, amputees would ...

A good night's sleep rests on your spine's biomechanics

May 22, 2017

A three-year study by QUT biomedical researchers in the Paediatric Spine Research Group (PSRG) aims to deepen our understanding of the concepts of comfort by using new techniques to look at how the spine reacts in different ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.