Long-term mortality risk low after cerebral vein thrombosis

July 12, 2012
Long-term mortality risk low after cerebral vein thrombosis
For patients who survive a cerebral vein thrombosis, the long-term risk of mortality and recurrent venous thromboembolism seems to be low, according to a study published in the July issue of the Journal of Thrombosis and Haemostasis.

(HealthDay) -- For patients who survive a cerebral vein thrombosis (CVT), the long-term risk of mortality and recurrent venous thromboembolism (VTE) seems to be low, according to a study published in the July issue of the Journal of Thrombosis and Haemostasis.

Francesco Dentali, M.D., from the University of Insubria in Varese, Italy, and colleagues retrospectively assessed long-term , residual disability, and recurrent VTE in an international cohort of 706 patients (73.7 percent female) with a first CVT episode who were followed for a median of 40 months (range, six to 297 months).

Over the follow-up period, the researchers found that 2.8 percent of patients died, 89.1 percent had a complete recovery (modified Rankin Score [mRS], 0 to 1), and 3.8 percent had a partial recovery and were independent (mRS, 2). The mean treatment duration was 12 months, during which time 84 percent of patients were treated with oral anticoagulants. CVT recurred in 4.4 percent of patients, and 6.5 percent had VTE in a different site, corresponding with an overall incidence of recurrence of 23.6 events per 1,000 patient-years and of 35.1 events per 1,000 patient years after anticoagulant therapy withdrawal. The only significant predictor of in multivariate analysis was a previous VTE (hazard ratio, 2.70).

"The long-term risk of mortality and recurrent VTE appears to be low in patients who survived the acute phase of CVT," the authors write.

Explore further: Higher risk of VTE in CKD surgical patients on enoxaparin

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Higher risk of VTE in CKD surgical patients on enoxaparin

June 8, 2012
(HealthDay) -- For patients with chronic kidney disease (CKD) who undergo total hip replacement (THR), the rate of major venous thromboembolism (VTE) is significantly higher in those treated with enoxaparin compared to those ...

Venous thromboembolism up in adult hospitalizations

June 8, 2012
(HealthDay) -- Every year, more than half a million hospitalized U.S. adults acquire venous thromboembolism (VTE), a growing public health concern that is often preventable, according to research published in the June 8 issue ...

ACP recommends new approach to prevent venous thromboembolism in hospitalized patients

October 31, 2011
In a new clinical practice guideline published today in Annals of Internal Medicine, the American College of Physicians (ACP) recommends that doctors assess the risk of thromboembolism and bleeding in patients hospitalized ...

In colorectal surgery, risk for blood clots appears higher with open method versus laparoscopy

June 20, 2011
The risk of developing venous thromboembolism (VTE) may be nearly twice as high for patients undergoing open surgery for colorectal problems, versus those undergoing laparoscopic colorectal (LC) resections, according to a ...

Study confirms some contraceptive pills more likely to cause blood clots

October 25, 2011
A study published in the British Medical Journal today confirms previous findings that certain oral contraceptive pills are more likely to cause serious blood clots (venous thromboembolism - VTE ) than others.

Recommended for you

Study opens new avenue in quest to develop tuberculosis vaccine

November 24, 2017
A team of scientists led by the University of Southampton has taken an important step forward in research efforts that could one day lead to an effective vaccine against the world's deadliest infectious disease.

Four simple tests could help GPs spot pneumonia and reduce unnecessary antibiotics

November 23, 2017
Testing for fever, high pulse rate, crackly breath sounds, and low oxygen levels could be key to helping GPs distinguish pneumonia from less serious infections, according to a large study published in the European Respiratory ...

New approach to tracking how deadly 'superbugs' travel could slow their spread

November 22, 2017
Killer bacteria - ones that have out-evolved our best antibiotics—may not go away anytime soon. But a new approach to tracking their spread could eventually give us a fighting chance to keep their death toll down.

Research points to diagnostic test for top cause of liver transplant in kids

November 22, 2017
Biliary atresia is the most common cause of liver transplants for children in the United States. Now researchers report in Science Translational Medicine finding a strong biomarker candidate that could be used for earlier ...

Alcohol consumption and metabolic factors act together to increase the risk of severe liver disease

November 22, 2017
A new study provides insights into the interaction between alcohol consumption and metabolic factors in predicting severe liver disease in the general population. The findings, which are published in Hepatology, indicate ...

Metabolites altered in chronic kidney disease

November 22, 2017
Chronic kidney disease (CKD) affects 1 in 7 people in the United States, according to the U.S. National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK). These individuals have a very high risk of cardiovascular ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.