New diagnostic definition of myocardial infarction issued

August 28, 2012
New diagnostic definition of myocardial infarction issued
An updated universal definition of myocardial infarction includes detection of a rise and/or fall in cardiac biomarker values, preferably cardiac troponin, according to a statement published online Aug. 26 in Circulation to coincide with presentation at the annual European Society of Cardiology Congress, held from Aug. 25 to 29 in Munich.

(HealthDay)—An updated universal definition of myocardial infarction (MI) includes detection of a rise and/or fall in cardiac biomarker values, preferably cardiac troponin (cTn), according to a statement published online Aug. 26 in Circulation to coincide with presentation at the annual European Society of Cardiology Congress, held from Aug. 25 to 29 in Munich.

Kristian Thygesen, Ph.D., from the Aarhus University Hospital in Denmark, and colleagues on the Joint /American College of Cardiology Foundation//World Heart Federation Task Force for the Universal Definition of created the revised definition to be used to better diagnose patients and define clinical trial end points.

The Joint Task Force defined an acute MI as evidence of consistent with acute myocardial ischemia. In this case, the criteria for MI are met with detection of a rise and/or fall of cardiac biomarker values, ideally cTn, with one or more value above the 99th percentile upper reference limit, in conjunction with at least one of the following: symptoms of ischemia; new or presumed new significant ST-segment-T wave changes or new left bundle branch block; development of pathologic Q waves; imaging evidence of new loss of myocardium or abnormality of regional wall motion; or identification of an intracoronary thrombus. In addition, specific criteria are provided for percutaneous coronary intervention-, stent thrombosis-, and grafting-related MIs.

"This is a truly global document that will be used worldwide," Thygesen said in a statement. "It will help doctors diagnose their patients so that they can provide the most appropriate treatment, and help researchers design clinical trials with standardized end points."

Several Task Force members and additional contributors disclosed financial ties to the pharmaceutical and biomedical industries.

Explore further: Tests for biomarker may help determine diagnosis of heart attack within hours

More information: Full Text
More Information

Related Stories

Tests for biomarker may help determine diagnosis of heart attack within hours

December 27, 2011
For patients admitted to an emergency department with chest pain, use of a contemporary or highly sensitive test for levels of troponin I (a protein in muscle tissue) may help rule-out a diagnosis of heart attack, while changes ...

Solution does not reduce rate of progression to development of heart attack after chest pain

March 27, 2012
Patients experiencing symptoms such as chest pain who received from paramedics an intravenous solution consisting of glucose-insulin-potassium (GIK) had no reduction in the rate of progression to heart attack and no improvement ...

QRS width on ECG linked to sudden cardiac arrest in CAD

April 20, 2012
(HealthDay) -- For patients with coronary artery disease (CAD), QRS width on electrocardiogram and echocardiographic evidence of heart failure are associated with out-of-hospital sudden cardiac arrest (SCA), regardless of ...

Long-term outcome similar with thrombus aspiration and stents in PCI

May 2, 2012
New research confirms thrombus aspiration (TA) during percutaneous coronary intervention (PCI) in patients with acute ST-segment elevation myocardial infarction (STEMI) provides long-term outcomes similar to conventional ...

Uric acid levels predict death in acute coronary syndrome

April 20, 2012
(HealthDay) -- Elevated uric acid levels are predictive of one-year mortality in patients with acute coronary syndrome, according to a study published in the May 1 issue of The American Journal of Cardiology.

Recommended for you

Gene therapy improved left ventricular and atrial function in heart failure by up to 25 percent

September 25, 2017
Heart function improved by up to 25 percent in a trial using gene therapy to reverse cardiac damage from congestive heart failure in a large animal model, Mount Sinai researchers report. This is the first study using a novel ...

Tension makes the heart grow stronger

September 25, 2017
By taking videos of a tiny beating zebrafish heart as it reconstructs its covering in a petri dish, scientists have captured unexpected dynamics of cells involved in tissue regeneration. They found that the depleted heart ...

Hospital mortality rates after heart attack differ by age

September 25, 2017
Outcomes for older patients hospitalized for a heart attack are often used as a measure of hospital quality for all patients. But a study led by Yale researchers shows that hospital mortality rates for older patients with ...

Laser device placed on the heart identifies insufficient oxygenation better than other measures

September 20, 2017
A new device can assess in real time whether the body's tissues are receiving enough oxygen and, placed on the heart, can predict cardiac arrest in critically ill heart patients, report researchers at Boston Children's Hospital ...

Metabolism switch signals end for healing hearts

September 19, 2017
Researchers have identified the process that shuts down the human heart's ability to heal itself, and are now searching for a drug to reverse it.

Beta blockers not needed after heart attack if other medications taken

September 18, 2017
A new study from the University of North Carolina at Chapel Hill finds beta blockers are not needed after a heart attack if heart-attack survivors are taking ACE inhibitors and statins. The study is the first to challenge ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.