Genetic counseling doesn't affect pre-diabetes behavior

September 7, 2012
Genetic counseling doesn't affect pre-diabetes behavior
Receiving genetic risk counseling does not significantly alter self-reported motivation or prevention program adherence for overweight individuals at risk for type 2 diabetes, according to a study published online Aug. 28 in Diabetes Care.

(HealthDay)—Receiving genetic risk counseling does not significantly alter self-reported motivation or prevention program adherence for overweight individuals at risk for type 2 diabetes, according to a study published online Aug. 28 in Diabetes Care.

Richard W. Grant, M.D., M.P.H., from Kaiser Permanente Northern California in Oakland, and colleagues conducted a randomized trial in which 108 overweight patients (mean age, 57.9 years) at increased phenotypic risk for type 2 diabetes were assigned to receive genetic testing or not. Thirty-six were used to assess genetic risk. Individual was provided to participants in the top (42 participants) and bottom (32 participants) score quartiles prior to being enrolled, together with 34 untested controls, in a 12-week validated diabetes prevention program. Middle-risk quartile participants were not included in the study.

The researchers found that participants attended 6.8 ± 4.3 group sessions and lost 8.5 ± 10.1 pounds, with 30.6 percent of participants losing ≥5 percent body weight. Comparing higher-risk recipients and lower-risk recipients with control subjects who did not receive counseling, there were few statistically significant differences in self-reported motivation, program attendance, or mean weight loss.

"In summary, a diabetes genetic risk assessment and counseling intervention for based on 36 single nucleotide polymorphisms neither improved nor substantially detracted from an evidence-based behavioral intervention to prevent diabetes," the authors write.

Explore further: Waist circumference linked to diabetes risk, independently of body mass index

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Waist circumference linked to diabetes risk, independently of body mass index

June 5, 2012
A collaborative re-analysis of data from the InterAct case-control study conducted by Claudia Langenberg and colleagues has established that waist circumference is associated with risk of type 2 diabetes, independently of ...

Primary care-based weight intervention helps obese patients reduce weight

November 14, 2011
Can a visit to your primary care doctor help you lose weight? Primary care physicians, working with medical assistants in their practices, helped one group of their obese patients lose an average of 10.1 lb during a two-year ...

Experimental drug helps diabetes patients lose weight

June 25, 2012
An experimental drug helped significantly more overweight patients with diabetes shed pounds, compared with placebo, a new study finds. The results will be presented at The Endocrine Society's 94th Annual Meeting in Houston.

Recommended for you

Smart mat detects early warning signs of foot ulcers

August 16, 2017
While completing his residency in anesthesiology at Massachusetts General Hospital in the mid-2000s, Jon Bloom saw his fair share of foot amputations among patients with diabetes. The culprit: infected foot ulcers.

The best place to treat type 1 diabetes might be just under your skin

August 14, 2017
A group of U of T researchers have demonstrated that the space under our skin might be an optimal location to treat type 1 diabetes (T1D).

New measure of insulin-making cells could gauge diabetes progression, treatment

August 10, 2017
Researchers at the University of Wisconsin-Madison have developed a new measurement for the volume and activity of beta cells, the source of the sugar-regulating hormone insulin.

Pioneering immunotherapy shows promise in type 1 diabetes

August 9, 2017
It may be possible to 'retrain' the immune system to slow the progression of type 1 diabetes, according to results of a clinical trial published today in the journal Science Translational Medicine.

Online team-based game helps patients with diabetes lower blood glucose

August 8, 2017
Researchers from Brigham and Women's Hospital and the Veterans Affairs Boston Healthcare System have found that an online, team-based game designed to teach patients about diabetes self-management had a sustained and meaningful ...

Oxidative stress biomarkers don't always signal diabetes risk

August 7, 2017
High levels of compounds found in the body that are commonly associated with oxidative damage may actually be a good sign for some people, according to a recent review of multiple human studies led by an epidemiologist at ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.