Marital status, race increase survival rate significantly for Stage III non-small cell lung cancer patients

September 6, 2012, American Society for Radiation Oncology

A study of survival data for Stage III, non-small cell lung cancer (NSCLC) patients at the University of Maryland's Greenebaum Cancer Center in Baltimore indicates that marital status and race can significantly impact patient survival rates, according to research presented at the 2012 Chicago Multidisciplinary Symposium in Thoracic Oncology. This symposium is sponsored by the American Society of Clinical Oncology (ASCO), the American Society for Radiation Oncology (ASTRO), the International Association for the Study of Lung Cancer (IASLC), and The University of Chicago.

This study reviewed the records of 168 patients with NSCLC who were treated with curative intent using chemotherapy and radiation at the Greenebaum Cancer Center from January 2000 to December 2010. The median survival rate for all patients was 13 months, with three-year survival rates of 21 percent.

Married women had the best three-year survival rate of 46 percent, and single men had the worst three-year survival rate of 3 percent. Married patients had improved survival compared to single patients—33 percent vs. 10 percent. Single females and married men had intermediate overall survival of 25 percent. Race also appears to play a role—married white patients had the best survival of 40 percent, and married black patients had a 26 percent three-year survival rate.

This study's results reinforce the critical role of spouses and caregivers in patient survival, and they are consistent with similar studies of other site-specific cancers, including head and neck and . The authors hypothesize that caregivers provide not only daily care but logistical support to help manage the treatment plan, compliance with the treatment plan and more accurate reporting of patient symptoms.

"While we were not surprised by these results, they confirm the positive impact of spousal support on patient survival," said lead author Elizabeth Nichols, MD, a resident in the department of at the University of Maryland Medical Center in Baltimore. "These findings also demonstrate the need for improved support of cancer patients and their spouses in order to continue to improve ."

Explore further: Married lung cancer patients survive longer than single patients after treatment

More information: The abstract, "Marital Status is an Independent Predictor of Survival for Patients Undergoing Definitive Chemoradiation for Stage III Non-Small Cell Lung Cancer," will be presented during the Poster Viewing at 5:00 p.m., Central time on September 6, 2012.

Related Stories

Married lung cancer patients survive longer than single patients after treatment

September 6, 2012
Married patients with locally advanced lung cancer are likely to survive longer after treatment than patients who are single, according to a study by researchers at the University of Maryland Marlene and Stewart Greenebaum ...

Brain radiation after lung cancer treatment reduces risk of cancer spreading

September 6, 2012
Stage III non-small cell lung cancer (NSCLC) patients treated with surgery and/or radiation therapy have a significantly reduced risk of developing brain metastases if they also receive prophylactic cranial irradiation (PCI); ...

Hispanic lung cancer patients have higher survival than non-Hispanic white patients

September 6, 2012
Analysis of non-small cell lung cancer (NSCLC) patient records in the California Cancer Registry (CCR) database during the 20-year period of 1988-2008 indicates that Hispanics/Latinos with NSCLC have a higher overall survival ...

Adding bavituximab to second-line chemotherapy doubles response rate

September 6, 2012
Adding the monoclonal antibody bavituximab to docetaxel chemotherapy doubles overall response rate and improves progression-free survival and overall survival in late-stage non-squamous, non-small cell lung cancer (NS-NSCLC) ...

Stage I NSCLC patients who receive radiation therapy are surviving longer

September 6, 2012
Stage I, non-small cell lung cancer (NSCLC) patients who received radiation therapy have an increased median survival of 21 months compared to 16 months, and the percentage of patients who receive no treatment declined from ...

Standard chemotherapy provides higher survival rate than experimental in lung cancer patients

September 6, 2012
Treatment with pemetrexed, carboplatin and bevacizumab followed by maintenance pemetrexed and bevacizumab (Pem+Cb+B) is no better than standard therapy with paclitaxel, carboplatin and bevacizumab followed by bevacizumab ...

Recommended for you

Researchers develop swallowable test to detect pre-cancerous Barrett's esophagus

January 17, 2018
Investigators at Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center have developed a simple, swallowable test for early detection of Barrett's esophagus that offers promise ...

Scientists zoom in to watch DNA code being read

January 17, 2018
Scientists have unveiled incredible images of how the DNA code is read and interpreted—revealing new detail about one of the fundamental processes of life.

Presurgical targeted therapy delays relapse of high-risk stage 3 melanoma

January 17, 2018
A pair of targeted therapies given before and after surgery for melanoma produced at least a six-fold increase in time to progression compared to standard-of-care surgery for patients with stage 3 disease, researchers at ...

Dulling cancer therapy's double-edged sword

January 17, 2018
Researchers have discovered that killing cancer cells can actually have the unintended effect of fueling the proliferation of residual, living cancer cells, ultimately leading to aggressive tumor progression.

T-cells engineered to outsmart tumors induce clinical responses in relapsed Hodgkin lymphoma

January 16, 2018
WASHINGTON-(Jan. 16, 2018)-Tumors have come up with ingenious strategies that enable them to evade detection and destruction by the immune system. So, a research team that includes Children's National Health System clinician-researchers ...

More evidence of link between severe gum disease and cancer risk

January 16, 2018
Data collected during a long-term health study provides additional evidence for a link between increased risk of cancer in individuals with advanced gum disease, according to a new collaborative study led by epidemiologists ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.