Dengue vaccine to be tested in India

November 19, 2012

French health care giant Sanofi Pasteur will soon test a vaccine against dengue fever in India amid concerns about the increasingly global spread of the disease, reports said Monday.

The vaccine will be tried on about 120 adults followed by trials on children before it can be made available internationally as soon as 2015, the Times of India newspaper said.

"Sites for the vaccine's final trials will stretch from Thailand to India as this vaccine has to work on populations across countries. We will test it in India soon," Sanofi's CEO Christopher Viehbacher was quoted as saying.

Dengue causes a flu-like illness for most victims but one of its strains can cause life-threatening internal bleeding.

There is no licensed vaccine to protect against dengue. Efforts to develop one have been complicated by the fact that there are four different strains, all of which may circulate in an outbreak zone.

Dengue also seems to be exclusive to humans, which means it is impossible to test vaccines on first.

Jean Lang, head of the vaccine's research and development programme, said Sanofi had been asked to conduct "phase two safety trials" in India by the national drug controller.

"It will help us get a licence to market the in India faster if it has been tested on the Indian population and is found safe and effective," Lang told the paper.

According to the UN's , between 50 and 100 million dengue infections occur each year in more than 100 countries. In 1970 the disease was endemic in just nine countries.

India, with a teeming population of 1.2 billion, has become a major focal point for the mosquito-borne viral infection.

Between 2007 and this month, the country has had 32,263 dengue cases with 188 deaths, according to the National Control Programme. Experts say the real numbers are much higher.

Explore further: Progress reported with candidate dengue vaccine

Related Stories

Progress reported with candidate dengue vaccine

July 25, 2012
Trials in Thailand with a candidate vaccine for dengue, a potentially fatal mosquito-borne disease, have shown it to protect against three of the four virus strains, its French maker said Wednesday.

Scientists make dengue vaccine breakthrough

September 10, 2012
Dengue is one of the most widespread mosquito-borne viral diseases in the world, with WHO estimating that around half of the world's population are currently at risk. While infection usually causes flu-like symptoms, it can ...

Concerns over cost of dengue vaccine lessened with new study

June 28, 2012
Research funded by the Dengue Vaccine Initiative (DVI) involving an economic analysis of producing a tetravalent dengue vaccine shows that the cost could be as low as $0.20 per dose with an annual production level of 60 million ...

Recommended for you

Research examines lung cell turnover as risk factor and target for treatment of influenza pneumonia

July 24, 2017
Influenza is a recurring global health threat that, according to the World Health Organization, is responsible for as many as 500,000 deaths every year, most due to influenza pneumonia, or viral pneumonia. Infection with ...

Scientists propose novel therapy to lessen risk of obesity-linked disease

July 24, 2017
With obesity related illnesses a global pandemic, researchers propose in the Journal of Clinical Investigation using a blood thinner to target molecular drivers of chronic metabolic inflammation in people eating high-fat ...

Raccoon roundworm—a hidden human parasite?

July 24, 2017
The raccoon that topples your trashcan and pillages your garden may leave more than just a mess. More likely than not, it also contaminates your yard with parasites—most notably, raccoon roundworms (Baylisascaris procyonis).

Google searches can be used to track dengue in underdeveloped countries

July 20, 2017
An analytical tool that combines Google search data with government-provided clinical data can quickly and accurately track dengue fever in less-developed countries, according to new research published in PLOS Computational ...

MRSA emerged years before methicillin was even discovered

July 19, 2017
Methicillin resistant Staphylococcus aureus (MRSA) emerged long before the introduction of the antibiotic methicillin into clinical practice, according to a study published in the open access journal Genome Biology. It was ...

New test distinguishes Zika from similar viral infections

July 18, 2017
A new test is the best-to-date in differentiating Zika virus infections from infections caused by similar viruses. The antibody-based assay, developed by researchers at UC Berkeley and Humabs BioMed, a private biotechnology ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.