Asthmatics at increased risk of pulmonary embolism

December 19, 2012, European Lung Foundation

People with asthma have an increased risk of pulmonary embolism, according to new research.

A new study, published online ahead of print today (20 December 2012) in the , looked at whether people with moderate or severe asthma had an increased risk of developing deep vein thrombosis, or pulmonary embolism.

Pulmonary embolism is when the of the lung or the bronchi becomes blocked. It usually results from deep vein thrombosis; a blood clot in the veins, which can break off and move around the body to the lung.

Previous research has found links between chronic lung diseases and blood clots, such as deep vein thrombosis, but this is the first study to look at any potential links with asthma.

The study examined 648 people with asthma in the Netherlands. All participants were aged between 18 and 88 years. Researchers examined participants' history of asthma and the medication they used to control their symptoms, along with any previous diagnoses of pulmonary embolism or . They compared these results to people without asthma.

The results demonstrated that people with severe asthma were almost 9 times more at risk of pulmonary embolism, compared to the general population. In addition, people with mild-moderate asthma tended to have a 3.5-times increased risk of pulmonary embolism. The study also identified as a potential risk factor for pulmonary embolism.

Lead author, Dr Christof Majoor, from the Academic Medical Centre in Amsterdam, the Netherlands, said: "This is the first time a link has been found between asthma and pulmonary embolism and we believe these results have important . Our findings suggest that people with severe asthma have an increased risk of and doctors should increase their awareness of the possibility of this occurrence in order to help prevent this serious event."

Explore further: Clot-busters safe for treating moderate pulmonary embolism

More information: Risk of deep-vein thrombosis and pulmonary embolism in asthma Authors: C. Majoor, P. Kamphuisen, A. Zwinderman, A. ten-Brinke, M. Amelink, L. Rijssenbeek-Nouwens, P. Sterk, H. Buller, E. Bel DOI: 10.1183/09031936.00150312

Related Stories

Clot-busters safe for treating moderate pulmonary embolism

March 27, 2012
Pulmonary embolism -- the sudden blockage of an artery in the lung -- is estimated to cause over 100,000 deaths each year in the U.S. Although thrombolytics, or "clot-buster" drugs, are currently reserved to treat only the ...

Xarelto's approval expanded

November 5, 2012
(HealthDay)—Approval of the anti-clotting drug Xarelto (rivaroxaban) has been expanded by the U.S. Food and Drug Administration to include treating deep vein thrombosis (DVT) or pulmonary embolism.

Risk of pulmonary embolism greatest during first week following total joint replacement

February 7, 2012
The elevated risk of pulmonary embolism (PE) – a blood clot that travels from the leg to the lungs – following total joint replacement (TJR) surgery has been well established, yet little is known about the natural ...

Recommended for you

Chronic inflammation causes loss of muscle mass during aging

January 12, 2018
People start losing muscle mass at the age of 40—about some 10 percent of the total muscle mass for each 10-year period, which may lead to fall-related injuries, slowing metabolism and reduced quality of life. Today, very ...

Breathing exercises help asthma patients with quality of life

December 13, 2017
A study led by the University of Southampton has found that people who continue to get problems from their asthma, despite receiving standard treatment, experience an improved quality of life when they are taught breathing ...

Study highlights the need for research into prevention of inflammatory bowel disease

December 7, 2017
Countries in Africa, Asia, the Middle East and South America have seen a rise in incidence of inflammatory bowel disease as they have become increasingly industrialised and westernised, a new study has found.

Air pollution can increase asthma risk in adults, even at low levels

November 24, 2017
Living close to a busy road can be bad for your respiratory health if you are middle aged, new Australian research has found.

Evidence found of oral bacteria contributing to bowel disorders

October 20, 2017
(Medical Xpress)—An international team of researchers has found evidence that suggests certain types of oral bacteria may cause or exacerbate bowel disorders. In their paper published in the journal Science, the group describes ...

New compound discovered in fight against inflammatory disease

September 22, 2017
A 10-year study by University of Manchester scientists for a new chemical compound that is able to block a key component in inflammatory illness has ended in success.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.