No evidence that doping enhances athletic performance

December 10, 2012
No evidence that doping enhances athletic performance
Although use of recombinant human erythropoietin is prohibited among athletes because it reportedly enhances performance, there is no scientific evidence that it does so, according to a study published online Dec. 6 in the British Journal of Clinical Pharmacology.

(HealthDay)—Although use of recombinant human erythropoietin (rHuEPO) is prohibited among athletes because it reportedly enhances performance, there is no scientific evidence that it does so, according to a study published online Dec. 6 in the British Journal of Clinical Pharmacology.

Jules A.A.C. Heuberger, from Leiden University in the Netherlands, and colleagues reviewed 13 studies in the scientific and medical literature examining the effect of rHuEPO on .

The researchers found that no study specifically addressed . Most studies used forms of rHuEPO with half-lives similar to endogenous erythropoietin. Only eight studies were placebo controlled, and only five of these were reported to be double-blinded. Hemoglobin concentration, hematocrit, and increased after rHuEPO treatment. However, the authors note that the only parameters associated with enhanced performance are lactate threshold, respiratory compensation point, and work economy. In addition, published case reports have linked rHuEPO to adverse cardiovascular effects among cyclists.

"rHuEPO use in cycling is rife but scientifically unsupported by evidence and its use in sports is medical malpractice," Heuberger and colleagues conclude. "The situation with rHuEPO use in athletes is analogous to the many forms of non-evidence-based treatments that exist in medical practice and which by common opinion should be refuted or confirmed by good clinical trials with real life end points."

Explore further: EPO doping in elite cycling: No evidence of benefit, but high risk of harm

More information: Abstract
Full Text

Related Stories

EPO doping in elite cycling: No evidence of benefit, but high risk of harm

December 5, 2012
The drug erythropoietin, often called EPO, is banned from sports because it is believed to enhance an athlete's performance and give people who use it an unfair advantage over unenhanced competitors. However a new systemic ...

The challenges and rewards of Paralympic medicine

July 5, 2012
In the Lancet paper, "Paralympic medicine," Nick Webborn of the British Paralympic Association and Peter Van de Vliet of the International Paralympic Committee Medical and Scientific Department, outline some of the issues ...

Asthma is the most common chronic disease among Olympic athletes

July 31, 2012
Based on data from the last five Olympic games, a study by the University of Western Australia has identified those athletes with asthma and airway hyper-responsiveness. With a prevalence of around 8% they are the most common ...

Higher pain tolerance in athletes may hold clues for pain management

May 17, 2012
Stories of athletes bravely "playing through the pain" are relatively common and support the widespread belief that they experience pain differently than non-athletes. Yet, the scientific data on pain perception in athletes ...

Recommended for you

In most surgery patients, length of opioid prescription, number of refills spell highest risk for misuse

January 17, 2018
The possible link between physicians' opioid prescription patterns and subsequent abuse has occupied the attention of a nation in the throes of an opioid crisis looking for ways to stem what experts have dubbed an epidemic. ...

Patients receive most opioids at the doctor's office, not the ER

January 16, 2018
Around the country, state legislatures and hospitals have tightened emergency room prescribing guidelines for opioids to curb the addiction epidemic, but a new USC study shows that approach diverts attention from the main ...

FDA bans use of opioid-containing cough meds by kids

January 12, 2018
(HealthDay)—Trying to put a dent in the ongoing opioid addiction crisis, the U.S. Food and Drug Administration on Thursday slapped strict new restrictions on the use of opioid-containing cold and cough products by kids.

Taking ibuprofen for long periods found to alter human testicular physiology

January 9, 2018
A team of researchers from Denmark and France has found that taking regular doses of the pain reliever ibuprofen over a long period of time can lead to a disorder in men called compensated hypogonadism. In their paper published ...

Nearly one-third of Canadians have used opioids: study

January 9, 2018
Nearly one in three Canadians (29 percent) have used "some form of opioids" in the past five years, according to data released Tuesday as widespread fentanyl overdoses continue to kill.

Growing opioid epidemic forcing more children into foster care

January 8, 2018
The opioid epidemic has become so severe it's considered a national public health emergency. Addiction to prescription painkillers, such as oxycodone and morphine, has contributed to a dramatic rise in overdose deaths and ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.