Antibiotic resistance 'has the potential to undermine modern health systems', say experts

March 11, 2013

Antibiotic resistance "has the potential to undermine modern health systems," argue health economists Richard Smith and Joanna Coast on bmj.com today. They believe that an increase in resistant organisms coupled with a big fall in the number of new antimicrobial drugs "suggests an apocalyptic scenario may be looming."

Their warning comes as the Chief Medical Officer launches the UK's Strategy and Action Plan, reflecting the need for a clear change in our understanding of and response to antimicrobial resistance by the public, NHS and government.

Current estimates suggest that antibiotic resistance is a relatively cheap problem, they write, but such estimates do not take account of the fact that antimicrobial medicines are integral to modern healthcare. For example, antibiotics are given as standard to patients undergoing surgery, to women delivering by , and to those having cancer treatment.

"From cradle to grave, have become pivotal in safeguarding the overall health of human societies," they write.

Although it is difficult to forecast the likely of resistance, they believe that even the highest current "provide false reassurance" and this may mean that inadequate attention and resources are devoted to resolving the problem.

For example, current infection rates for patients undergoing hip replacement are 0.5-2%, so most patients recover without infection, and those who have an infection have it successfully treated. But the authors estimate that, without antibiotics, the rate of postoperative infection could be 40-50% and about 30% of those with an infection could die.

While they recognise that this is a simplistic analysis, they say "we use it as an example to illustrate and provoke, to emphasise the point that infection rates and their consequences in terms of health service costs and human health may be unimaginable."

A change in culture and action is needed to plan for a future with more , they conclude. "Waiting for the burden to become substantial before taking action may mean waiting until it is too late. Rather than see expenditure on antimicrobial policies as a cost, we should think of it as an insurance policy against a catastrophe; albeit one which we hope will never happen."

In an accompanying editorial, Professors Anthony Kessel and Mike Sharland say the new UK Five Year Antimicrobial Resistance Strategy and Action Plan "represents an important step in both recognising and responding to this significant threat."

The problems are global and the terminology complex, but the importance is clear, they write. "A fundamental standard of the NHS should include basic high quality routine infection control and clinical care, as noted by the Francis inquiry. These standards of care are crucial to the prevention and control of all healthcare associated infections, including multi-drug resistant Gram negative bacteria."

Explore further: Infection prevention groups outline steps needed to preserve antibiotics

Related Stories

The rising threat of antibiotic resistance

January 10, 2013

A major European and global health issue is resistance to or inappropriate use of antibiotics. The European Centre for Disease Prevention and Control (ECDC) estimates that each year, antimicrobial resistance (AMR) results ...

Recommended for you

Listeria may be serious miscarriage threat early in pregnancy

February 21, 2017

Listeria, a common food-borne bacterium, may pose a greater risk of miscarriage in the early stages of pregnancy than appreciated, according to researchers at the University of Wisconsin-Madison School of Veterinary Medicine ...

Ebola linked to habitat destruction

February 20, 2017

A Massey University veterinary scientist has co-authored research suggesting that Ebola virus emergence is linked to the clearing of animal habitat through deforestation in West and Central Africa.

New study determines how long Zika remains in body fluids

February 20, 2017

A study published in the New England Journal of Medicine provides evidence that the Zika virus particles remain longer in blood than in urine and some other body fluids. This information suggests that blood serum may be the ...

Researcher helps stem the spread of superbugs

February 20, 2017

Katherine Baker feels vindicated. She and other microbiologists have been warning for years that anti-bacterial soaps containing triclosan are bad for the environment, harmful for health, and do nothing to prevent disease.

Scientists uncover how Zika virus causes microcephaly

February 17, 2017

A multidisciplinary team from The University of Texas Medical Branch at Galveston has uncovered the mechanisms that the Zika virus uses to alter brain development. These findings are detailed in Stem Cell Reports.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.