Using internet search logs can help identify drug interactions

March 28, 2013
Using internet search logs can help identify drug interactions
Search logs can be used to inexpensively mine for anonymized signals that may alert authorities to potential drug interactions and add new Web-scale pharmacovigilance capabilities, according to research published online March 6 in the Journal of the American Medical Informatics Association.

(HealthDay)—Search logs can be used to inexpensively mine for anonymized signals that may alert authorities to potential drug interactions and add new Web-scale pharmacovigilance capabilities, according to research published online March 6 in the Journal of the American Medical Informatics Association.

Ryen W. White, Ph.D., of Microsoft Research in Redmond, Wash., and colleagues conducted a large-scale study of Web search log data gathered in 2010 to determine whether early clues about a drug's adverse events might emerge from evaluating search terms.

Specifically, the investigators evaluated whether searches for paroxetine and pravastatin could have been used to predict a of . By examining drug pairs that are known to cause hyperglycemia and those that are not associated with hyperglycemia, they were able to determine that search logs can be used to inexpensively mine for anonymized signals that may improve drug safety surveillance.

"Overall, these findings demonstrate the potential value of the log analysis for identifying drug pairs linked to hyperglycemia and illustrate the generalizability of the method beyond just the pravastatin-paroxetine pairing," the authors write.

Explore further: Internet searches can identify drug safety issues well ahead of public alerts

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

TPN-linked hyperglycemia ups death for non-critically ill

January 3, 2013

(HealthDay)—Non-critically ill hospitalized patients who develop hyperglycemia after total parenteral nutrition (TPN) are more than five times more likely to die in the hospital, according to research published online Dec. ...

Daily exercise doesn't further improve glycemic control

March 14, 2012

(HealthDay) -- For individuals with type 2 diabetes, 30 minutes of moderate-intensity endurance exercise once a day or an hour every other day are equally effective for controlling hyperglycemia, according to a study published ...

Recommended for you

Researchers identify source of opioids' side effects

January 17, 2017

A commercially available drug may help drastically reduce two side effects of opioid painkillers—a growing tolerance and a paradoxical increased sensitivity to pain—without affecting the drugs' ability to reduce pain, ...

CVS generic competitor to EpiPen, sold at a 6th the price

January 12, 2017

CVS is now selling a rival, generic version of Mylan's EpiPen at about a sixth of its price, just months after the maker of the life-saving allergy treatment was eviscerated before Congress because of its soaring cost to ...

Many misuse OTC sleep aids: survey

December 29, 2016

(HealthDay)—People struggling with insomnia often turn to non-prescription sleep remedies that may be habit-forming and are only intended for short-term use, according to a new Consumer Reports survey.

The pill won't kill your sexual desire, researchers say

December 15, 2016

Taking the pill doesn't lower your sexual desire, contrary to popular belief, according to research published in the Journal of Sexual Medicine. The authors of the research, from the University of Kentucky and Indiana University ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.