Timing, duration of obesity impact adult diabetes risk

April 5, 2013
Timing, duration of obesity impact adult diabetes risk
The likelihood of diabetes in young adulthood is increased for those who are obese as adolescents and those with persistent obesity, compared to those with adult-onset obesity, according to a study published in the April issue of Diabetes Care.

(HealthDay)—The likelihood of diabetes in young adulthood is increased for those who are obese as adolescents and those with persistent obesity, compared to those with adult-onset obesity, according to a study published in the April issue of Diabetes Care.

Natalie S. The, Ph.D., from Furman University in Greenville, S.C., and colleagues followed a cohort of 10,481 individuals, aged 12 to 21 years, from the U.S. National Longitudinal Study of Adolescent Health over two visits at age 18 to 27 years and 24 to 33 years. The correlations of obesity timing and obesity duration over time with diabetes were assessed.

The researchers found that 4.4 percent of 24- to 33-year-old participants had diabetes, and about half were undiagnosed. The prevalence of diabetes was higher among blacks and Hispanics than among whites. Even after accounting for current , , and age at menarche, women who became obese before age 16 were significantly more likely to have diabetes, compared with those who became obese at or after age 18 (odds ratio [OR], 2.77) in multivariate analyses. For men and women, persistent obesity correlated with increased odds of diabetes (OR, 2.27 and 2.08).

"We found that (versus adult onset) and persistent obesity from adolescence to young adulthood conferred the greatest likelihood of diabetes in ," the authors write. "Our findings suggest that, in addition to current obesity, information about timing and duration of obesity are needed to fully understand and predict diabetes risk."

Explore further: Lifetime 'dose' of excess weight linked to risk of diabetes

More information: Abstract
Full Text

Related Stories

Lifetime 'dose' of excess weight linked to risk of diabetes

September 6, 2011
Obesity is a known risk factor for developing type 2 diabetes. But it hasn't been clear whether the "dose" of obesity—how much excess weight a person has, and for how long—affects the risk of diabetes.

Gestational diabetes, obesity impact pregnancy outcomes

March 2, 2012
(HealthDay) -- Women with gestational diabetes mellitus (GDM) who are obese have significantly higher odds of adverse pregnancy outcomes, according to findings from the multinational Hyperglycemia and Adverse Pregnancy Outcome ...

Effect of obesity gene variant influenced by age

January 31, 2013
(HealthDay)—A genetic variant associated with obesity risk (FTO) has a greater effect on body mass index (BMI) in young adults than older adults, according to a study published online Jan. 8 in Diabetes.

Recommended for you

Genetic discovery may help better identify children at risk for type 1 diabetes

January 17, 2018
Six novel chromosomal regions identified by scientists leading a large, prospective study of children at risk for type 1 diabetes will enable the discovery of more genes that cause the disease and more targets for treating ...

Women who have gestational diabetes in pregnancy are at higher risk of future health issues

January 16, 2018
Women who have gestational diabetes mellitus (GDM) during pregnancy have a higher than usual risk of developing type 2 diabetes, hypertension, and ischemic heart disease in the future, according to new research led by the ...

Diabetes gene found that causes low and high blood sugar levels in the same family

January 15, 2018
A study of families with rare blood sugar conditions has revealed a new gene thought to be critical in the regulation of insulin, the key hormone in diabetes.

Discovery could lead to new therapies for diabetics

January 12, 2018
New research by MDI Biological Laboratory scientist Sandra Rieger, Ph.D., and her team has demonstrated that an enzyme she had previously identified as playing a role in peripheral neuropathy induced by cancer chemotherapy ...

Enzyme shown to regulate inflammation and metabolism in fat tissue

January 11, 2018
The human body has two primary kinds of fat—white fat, which stores excess calories and is associated with obesity, and brown fat, which burns calories in order to produce heat and has garnered interest as a potential means ...

Big strides made in diabetes care

January 5, 2018
(HealthDay)—This past year was a busy, productive one for diabetes research and care.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.