Vascular markers linked to cognitive decline in diabetes

April 18, 2013
Vascular markers linked to cognitive decline in diabetes
Stroke and subclinical markers of macrovascular disease are associated with cognitive decline in older adults with type 2 diabetes, according to a study published online April 11 in Diabetes Care.

(HealthDay)—Stroke and subclinical markers of macrovascular disease are associated with cognitive decline in older adults with type 2 diabetes, according to a study published online April 11 in Diabetes Care.

Insa Feinkohl, from the University of Edinburgh in the United Kingdom, and colleagues measured signs of macrovascular disease in 831 cognitively healthy older adults with type 2 diabetes. Subjects underwent seven at baseline and after four years. Lifetime cognitive change was estimated by adjustment for vocabulary.

The researchers found a significant association between measures of cognitive decline and stroke, N-terminal probrain natriuretic peptide, ankle brachial index, and carotid intima-media thickness. There was a significant association between stroke and increased estimated lifetime cognitive decline, as well as between subclinical markers and actual four-year decline. Adjusting for had little effect. There was no association found between measures of cognitive decline and non-stroke vascular events.

"Stroke and subclinical markers of and generalized atherosclerosis are associated with in older patients with type 2 diabetes," Feinkohl and colleagues conclude.

The study was funded in part by Pfizer.

Explore further: Accelerated cognitive decline seen with T2DM in middle age

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Accelerated cognitive decline seen with T2DM in middle age

January 21, 2013
(HealthDay)—Middle-aged patients with type 2 diabetes show accelerated cognitive decline in information processing speed and executive function, according to a study published online Dec. 28 in Diabetes Care.

Vitamin D not tied to subclinical atherosclerosis in T1DM

April 12, 2013
(HealthDay)—For individuals with type 1 diabetes, low concentrations of vitamin D metabolites are not associated with an increased risk of subclinical atherosclerosis, according to a study published online March 25 in Diabetes ...

Tests to predict heart problems may be more useful predictor of memory loss than dementia tests

April 1, 2013
Risk prediction tools that estimate future risk of heart disease and stroke may be more useful predictors of future decline in cognitive abilities, or memory and thinking, than a dementia risk score, according to a new study ...

Vascular changes linked to dementia

July 21, 2011
The same artery-clogging process (atherosclerosis) that causes heart disease can also result in age-related vascular cognitive impairments (VCI), according to a new American Heart Association/American Stroke Association scientific ...

Diabetes, poor glucose control associated with greater cognitive decline in older adults

June 18, 2012
Among well-functioning older adults without dementia, diabetes mellitus (DM) and poor glucose control among those with DM are associated with worse cognitive function and greater cognitive decline, according to a report published ...

Recommended for you

Diabetes can be tracked with our Google searches

July 26, 2017
The emergence of Type 2 Diabetes could be more effectively monitored using our Google searches—helping public health officials keep track of the disease and halt its spread—according to research by the University of Warwick.

Scientists discover a new way to treat type 2 diabetes

July 21, 2017
Medication currently being used to treat obesity is also proving to have significant health benefits for patients with type 2 diabetes. A new study published today in Molecular Metabolism explains how this therapeutic benefit ...

Alzheimer's drug cuts hallmark inflammation related to metabolic syndrome by 25 percent

July 20, 2017
An existing Alzheimer's medication slashes inflammation and insulin resistance in patients with metabolic syndrome, a potential therapeutic intervention for a highly dangerous condition affecting 30 percent of adults in the ...

Diabetes or its precursor affects 100 million Americans

July 19, 2017
Almost one-third of the US population—100 million people—either has diabetes or its precursor condition, known as pre-diabetes, said a government report Tuesday.

One virus may protect against type 1 diabetes, others may increase risk

July 11, 2017
Doctors can't predict who will develop type 1 diabetes, a chronic autoimmune disease in which the immune system destroys the cells needed to control blood-sugar levels, requiring daily insulin injections and continual monitoring.

Diabetes complications are a risk factor for repeat hospitalizations, study shows

July 7, 2017
For patients with diabetes, one reason for hospitalization and unplanned hospital readmission is severe dysglycemia (uncontrolled hyperglycemia - high blood sugar, or hypoglycemia - low blood sugar), says new research published ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.