Dietary fiber intake linked to reduced gastric cancer risk

Dietary fiber intake linked to reduced gastric cancer risk
Dietary fiber intake is inversely associated with gastric cancer risk and is likely independent of conventional risk factors, according to a meta-analysis published in the July issue of Gastroenterology.

(HealthDay)—Dietary fiber intake is inversely associated with gastric cancer risk and is likely independent of conventional risk factors, according to a meta-analysis published in the July issue of Gastroenterology.

Zhizhong Zhang, from the Nanjing University School of Medicine in China, and colleagues conducted a literature review to identify case-control and cohort studies that assessed the correlation between dietary and gastric . Twenty-one articles were analyzed, which included 580,064 subjects. Summary relative risks were estimated using random-effects models.

The researchers found that, for the highest versus the lowest intake, the summary odds ratios of gastric cancer was 0.58, with significant heterogeneity identified among studies (I², 62.2 percent). Consistent results were seen on stratified analysis accounting for study design, geographic area, source and type of fiber, Lauren's classification, publication year, sample size, and study quality score. A significant, 44 percent reduction in gastric cancer risk was seen for each 10-g/day increment in fiber intake. Similar results were seen on restriction of sensitivity analysis to studies controlling for conventional risk factors. There was little effect on the combined risk estimate with omission of any single study.

"In a meta-analysis, we show that dietary fiber intake is associated inversely with risk; the effect probably is independent of conventional risk factors," the authors write. "The direction of the protective association of dietary fiber was consistent among all studies, but the absolute magnitude was less certain because of among the studies."


Explore further

Fatty acids found in fish linked to lower risk of breast cancer

More information: Abstract
Full Text (subscription or payment may be required)
Journal information: Gastroenterology

Health News Copyright © 2013 HealthDay. All rights reserved.

Citation: Dietary fiber intake linked to reduced gastric cancer risk (2013, July 23) retrieved 21 October 2019 from https://medicalxpress.com/news/2013-07-dietary-fiber-intake-linked-gastric.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
1 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more