Depression up in post-radiation head and neck cancer survivors
Allen M. Chen, M.D., from the University of California in Davis, and colleagues conducted a cross-sectional analysis involving 211 patients with squamous cell carcinoma of the head and neck, who had been previously treated with radiotherapy, to determine the prevalence of self-reported depression. Rates of depression were analyzed using the self-administered University of Washington Quality of Life Instrument.
The researchers observed no difference in the mean mood score at one, three, and five years after treatment. At one, three, and five years, respectively, 17, 15, and 13 percent of patients reported their mood as somewhat or extremely depressed. The presence of tracheostomy tube or laryngeal stoma, gastrostomy tube dependence, and continued smoking at follow-up correlated significantly with post-radiotherapy depression. At one, three, and five years of follow-up, the proportion of those who were somewhat or extremely depressed and were using antidepressants was 6, 11, and 0 percent, respectively, while 3, 6, and 0 percent, respectively, were actively undergoing psychotherapy and/or counseling.
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