Transcatheter valve implantation benefits even very elderly

January 10, 2014
Transcatheter valve implantation benefits even very elderly

(HealthDay)—Transcatheter aortic valve implantation is associated with acceptable clinical outcomes, even among very elderly patients, according to a study published in the January issue of the Annals of Thoracic Surgery.

Masanori Yamamoto, M.D., from the Centre Hospitalier Universitaire Henri Mondor in Créteil, France, and colleagues examined age-specific differences in clinical outcomes for 867 patients aged 80 to 84 years; 1,064 patients aged 85 to 89 years; and 349 patients aged ≥90 years. All patients were enrolled in the French national transcatheter aortic valve implantation registry.

The researchers observed no differences among groups in the rates of procedural success, complications, or length of hospitalization. There were no significant differences between the groups in cumulative 30-day (10.3, 9.5, and 11.2 percent, respectively, for those aged 80 to 84 years, 85 to 89 years, and ≥90 years; P = 0.53). No significant differences were seen in cumulative one-year mortalities, although the mortality rate was higher in patients aged 85 to 89 and ≥90 years compared with those aged 80 to 84 years (19.8 versus 26.1 and 27.7 percent, respectively; P = 0.16). Patient age (85 to 89 and ≥90 versus 80 to 84 years) was not associated with increased 30-day mortality risk (hazard ratios, 0.92 [P = 0.38] and 1.26 [P = 0.28], respectively) or with one-year mortality risk (hazard ratios, 1.16 [P = 0.25] and 1.36 [P = 0.073], respectively), after adjustment for baseline characteristics and potential confounders.

"Transcatheter implantation may be a good therapeutic option even in very elderly patients (85 to 89 years and ≥90 years)," the authors write.

Several authors disclosed financial ties to the medical device industry.

Explore further: Rate of aortic valve replacement for elderly patients has increased; outcomes improved

More information: Abstract
Full Text

Related Stories

Rate of aortic valve replacement for elderly patients has increased; outcomes improved

November 17, 2013
Jose Augusto Barreto-Filho, M.D., Ph.D., of the Federal University of Sergipe and the Clinica e Hospital Sao Lucas, Sergipe, Brazil, and colleagues assessed procedure rates and outcomes of surgical aortic valve replacement ...

Elderly discharged home do well after heart valve surgery

September 4, 2012
(HealthDay)—People over the age of 80 generally do well after aortic or mitral valve replacement surgery, especially if they are discharged home, according to a study published in the September issue of The Annals of Thoracic ...

TAVI feasible in bicuspid aortic valve

September 2, 2013
Transcatheter aortic valve implantation (TAVI) is feasible in patients with bicuspid aortic valve, according to research presented at ESC Congress 2013 today by Dr. Timm Bauer from Germany. The findings open up a new treatment ...

TAVI is safe alternative to redo cardiac surgery

September 2, 2013
TAVI is a safe alternative to redo cardiac surgery for failing bioprosthetic valves, according to research presented at the ESC Congress today by Dr. Spyridon Katsanos from the Netherlands. The findings suggest that transcatheter ...

Results of the REPRISE II trial reported

November 1, 2013
In a clinical trial, a second-generation transcatheter aortic valve demonstrated low rates of complications that are sometimes seen in transcatheter aortic valve replacement (TAVR), including challenges with positioning, ...

Results of the COREVALVE EXTREME RISK trial presented

October 29, 2013
In a clinical trial, a self-expanding transcatheter aortic valve met the key performance objective of reducing death and stroke in patients with severe aortic stenosis at "extreme risk" for surgery.Results of the COREVALVE ...

Recommended for you

Starting periods before age of 12 linked to heightened risk of heart disease and stroke

January 15, 2018
Starting periods early—before the age of 12—is linked to a heightened risk of heart disease and stroke in later life, suggests an analysis of data from the UK Biobank study, published online in the journal Heart.

'Decorated' stem cells could offer targeted heart repair

January 10, 2018
Although cardiac stem cell therapy is a promising treatment for heart attack patients, directing the cells to the site of an injury - and getting them to stay there - remains challenging. In a new pilot study using an animal ...

Two simple tests could help to pinpoint cause of stroke

January 10, 2018
Detecting the cause of the deadliest form of stroke could be improved by a simple blood test added alongside a routine brain scan, research suggests.

Exercise is good for the heart, high blood pressure is bad—researchers find out why

January 10, 2018
When the heart is put under stress during exercise, it is considered healthy. Yet stress due to high blood pressure is bad for the heart. Why? And is this always the case? Researchers of the German Centre for Cardiovascular ...

Heart-muscle patches made with human cells improve heart attack recovery

January 10, 2018
Large, human cardiac-muscle patches created in the lab have been tested, for the first time, on large animals in a heart attack model. This clinically relevant approach showed that the patches significantly improved recovery ...

Place of residence linked to heart failure risk

January 9, 2018
Location. Location. Location.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.