Psychological side-effects of anti-depressants worse than thought

February 25, 2014, University of Liverpool

A University of Liverpool researcher has shown that thoughts of suicide, sexual difficulties and emotional numbness as a result of anti-depressants may be more widespread than previously thought.

In a survey of 1,829 people who had been prescribed anti-depressants, the researchers found large numbers of people – over half in some cases – reporting on due to their medication, which has led to growing concerns about the scale of the problem of over-prescription of these drugs.

Psychologist and lead researcher, Professor John Read from the University's Institute of Psychology, Health and Society, said: "The medicalisation of sadness and distress has reached bizarre levels. One in ten people in some countries are now prescribed antidepressants each year.

"While the biological side-effects of antidepressants, such as weight gain and nausea, are well documented, the psychological and interpersonal effects have been largely ignored or denied. They appear to be alarmingly common."

Each person completed an online questionnaire which asked about twenty adverse effects. The study was carried out in New Zealand and all of the participants had been on anti-depressants in the last five years. The survey factored in people's levels of depression and asked them to report on how they had felt while taking the medication.

Over half of people aged 18 to 25 in the study reported suicidal feelings and in the total sample there were large percentages of people suffering from '' (62%) and 'feeling emotionally numb' (60%). Percentages for other effects included: 'feeling not like myself' (52%), 'reduction in positive feelings' (42%), 'caring less about others' (39%) and 'withdrawal effects' (55%). However, 82% reported that the drugs had helped alleviate their depression.

Professor Read concluded: "While the biological side-effects of antidepressants, such as weight gain and nausea, are well documented, psychological and interpersonal issues have been largely ignored or denied. They appear to be alarmingly common."

"Effects such as feeling emotionally numb and caring less about other people are of major concern. Our study also found that people are not being told about this when prescribed the drugs.

"Our finding that over a third of respondents reported suicidality 'as a result of taking the ' suggests that earlier studies may have underestimated the problem."

The research was published in the journal Psychiatry Research.

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5 / 5 (2) Feb 25, 2014
Anyone who knows someone that relies on antidepressants is probably familiar with these effects.

The only real question, therefore, is why has this gone unremarked after decades of widespread use?

I'm pretty sure we all know the answer.

1 / 5 (1) Feb 27, 2014
All antidepressants are poison and should be banned! Proper nutrition will cure depression, but the drug pushers don't want you to know this.
1 / 5 (1) Mar 01, 2014
I have been preaching against taking antidepressants for years. Society in whole has become afraid of sad feelings. Historically those who today would have been clinically diagnosed as depressed and medicated, have been those that have changed the world. Depressed people see a problem and want to solve it.
How about this, when you see someone depressed let them know as long as they don't let their depression affect anyone else, that it is ok and normal for some people to be depressed. Assure them they are normal, listen to them, comfort them. Just don't drug them.
5 / 5 (1) Mar 01, 2014
Depressed people see a problem and want to solve it.

No, depressed people generally lack the motivation to do anything productive. I know doctors sometimes prescribe antidepressants for sadness and I think that is drug abuse. It isn't candy. But if you have ever been truly depressed, you would know the sexual side effects, emotional numbing, manic episodes and weight gain are a small price to pay. You might be surprised just how much pain it is possible to feel and how little control you can have over it. I would welcome better drugs, but flawed though the current ones are, they are better than the other alternatives: suffering and suicide.
5 / 5 (1) Mar 01, 2014
All antidepressants are poison and should be banned! Proper nutrition will cure depression, but the drug pushers don't want you to know this.

Sorry, but I tried eating healthy, exercising, you name it, and was still depressed. That's the biggest myth out! I decided to start taking antidepressants, and they do help with the mood.

But they aren't without side effects (sexual, numbness etc). Only when you start taking them.
not rated yet Mar 02, 2014
No one sees a problem with them only surveying depressed people who were on medication?

Is there no control group? Is there no other depressed group who weren't taking medication? I can't take this seriously if there's not, though ideally what you'd want is a placebo group. How do we know it's not the depression itself causing these "side-effects"?

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