Anticoagulation seen in about half of sub-segmental PE cases

Anticoagulation seen in about half of sub-segmental PE cases

(HealthDay)—Sub-segmental pulmonary embolism (SSPE) represents a substantial burden of total pulmonary embolisms (PEs), according to research published online Dec. 1 in the Journal of Thrombosis and Haemostasis.

Jennifer Goy, M.D., from the University of British Columbia in Vancouver, Canada, and colleagues reviewed the charts of 2,213 patients who underwent pulmonary angiography in three (2009 to 2011). The authors sought to ascertain the frequency with which SSPE patients received therapy, as well as the incidences of bleeding complications and recurrent thrombosis.

The researchers observed 550 cases of PE (24.8 percent), with SSPEs accounting for the largest pulmonary filling defects (15 percent of identified PEs). An alternative diagnosis to PE was identified on computed tomography to explain the patients' symptoms in 55 of the 82 SSPE cases. Just over half of the SSPE patients (43) received anticoagulation. Of those receiving anticoagulation, major, life-threatening bleeding complications occurred in two patients. There were no cases of recurrent thrombosis in any SSPE patients, with or without anticoagulation.

"Randomized controlled trial data is needed to further investigate the risks and benefits of anticoagulation in patients with SSPE," the authors write.

One author disclosed financial ties to the pharmaceutical industry.

Explore further

Activity decreases bleeding risk from anticoagulation meds

More information: Abstract
Full Text (subscription or payment may be required)

Copyright © 2014 HealthDay. All rights reserved.

Citation: Anticoagulation seen in about half of sub-segmental PE cases (2014, December 10) retrieved 17 October 2019 from
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more