Cataract risk not down with long-tem selenium, vitamin E

January 9, 2015
Cataract risk not down with long-tem selenium, vitamin E

(HealthDay)—Long-term supplementation with selenium or vitamin E is not associated with a reduction in the risk of age-related cataract among men, according to a study published in the January issue of JAMA Ophthalmology.

William G. Christen, Sc.D., from Brigham and Women's Hospital in Boston, and colleagues examined the effect of long-term supplementation with and vitamin E on the incidence of cataract. Data were collected from the Selenium and Vitamin E Cancer Prevention Trial (SELECT) involving aged 50 years and older for African-American participants and 55 years and older for all other men. A total of 11,267 SELECT participants participated in the SELECT Eye Endpoints ancillary study.

The researchers identified 389 cases of cataract during a mean of 5.6 years of treatment and follow-up. There was no significant difference in the number of cataracts in the selenium versus the no selenium group (185 versus 204; hazard ratio, 0.91; 95 percent confidence interval, 0.75 to 1.11; P = 0.37). No difference was seen in the vitamin E treated group versus the placebo group (197 versus 192 cases; hazard ratio, 1.02; 95 percent confidence interval, 0.84 to 1.25; P = 0.81). Results were similar for cataract extraction.

"These data from a large cohort of apparently healthy men indicate that long-term daily supplementation with selenium and/or vitamin E is unlikely to have a large beneficial effect on age-related ," the authors write.

One author disclosed financial ties to Pfizer related to vitamins. Study agents, packaging, and multivitamins were provided by nutritional companies.

Explore further: Vitamin E, selenium supplements unlikely to effect age-related cataracts in men

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Vitamin E, selenium supplements unlikely to effect age-related cataracts in men

September 18, 2014
Taking daily supplements of selenium and/or vitamin E appears to have no significant effect on the development of age-related cataracts in men, writes Author William G. Christen, Sc.D., of Brigham & Women's Hospital and Harvard ...

Selenium and vitamin E supplementation over recommended dietary intake may raise prostate cancer risk

February 21, 2014
A multi-center study led by Fred Hutchinson Cancer Research Center has found that high-dose supplementation with both the trace element selenium and vitamin E increase the risk of high-grade prostate cancer. But importantly, ...

Smoking cessation reduces risk of cataract extraction

January 7, 2014
(HealthDay)—Smoking cessation correlates with a reduction in the risk of cataract extraction, although the risk persists for more than 20 years, according to a study published online Jan. 2 in JAMA Ophthalmology.

Long-term daily multivitamin supplement use decreases cataract risk in men

February 20, 2014
Long-term daily multivitamin supplement use may lower cataract risk in men, according to a study of nearly 15,000 male physicians published this month in Ophthalmology, the journal of the American Academy of Ophthalmology.

Cohort study indicates that selenium may be protective against advanced prostate cancer

April 10, 2013
A greater level of toenail selenium was associated with a significant decrease in the risk for advanced prostate cancer, according to data presented at the AACR Annual Meeting 2013, held in Washington, D.C., April 6-10.

Recommended for you

Combination of type 2 diabetes and sleep apnoea indicates eyesight loss within four years

July 4, 2017
Research led by the University of Birmingham has discovered that patients who suffer from both Type 2 diabetes and obstructive sleep apnoea are at greater risk of developing a condition that leads to blindness within an average ...

Nearly 60% of pinkeye patients receive antibiotic eye drops, but they're seldom necessary

June 28, 2017
A new study suggests that most people with acute conjunctivitis, or pinkeye, are getting the wrong treatment.

Magnetic implants used to treat 'dancing eyes'

June 26, 2017
A research team has successfully used magnets implanted behind a person's eyes to treat nystagmus, a condition characterised by involuntary eye movements.

Drug shows promise against vision-robbing disease in seniors

June 21, 2017
An experimental drug is showing promise against an untreatable eye disease that blinds older adults—and intriguingly, it seems to work in patients who carry a particular gene flaw that fuels the damage to their vision.

Reproducing a retinal disease on a chip

June 15, 2017
Approximately 80% of all sensory input is received via the eyes, so suffering from chronic retinal diseases that lead to blindness causes a significant decrease in the quality of life (QOL). And because retinal diseases are ...

New gene therapy for vision loss proven safe in humans

May 16, 2017
In a small and preliminary clinical trial, Johns Hopkins researchers and their collaborators have shown that an experimental gene therapy that uses viruses to introduce a therapeutic gene into the eye is safe and that it ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.