Feijoa and blackberry help reduce inflammation

January 6, 2015, University of Auckland

Feijoa and blackberry are two fruits with a strong anti-inflammatory effect that could help people with inflammatory diseases, according to recent research from the University of Auckland.

The research into treatments for investigated the anti-inflammatory and anti-oxidant properties of 12 fruits.

They tested mango, feijoa, elderberry, cranberry, blackcurrant, , red raspberry, strawberry, green grapes, plum, pear and black grapes.

"Most fruits are good for you and have some anti-oxidant effect, but feijoa and blackberry showed the strongest anti- in the experiments," says University of Auckland, Nutrition and Dietetics researcher, Professor Lynn Ferguson.

The study identified fruit compounds with an anti-inflammatory effect through certain chemical pathways that could be tested further to develop them as complementary therapies for inflammatory bowel disease and other inflammatory disorders.

"Inflammatory responses are important for coping with damage, but an over-active inflammatory response is also damaging and can create problems, says Professor Ferguson. "These responses can be debilitating for New Zealanders with an inflammatory disease, and these fruits can help to limit the inflammatory response."

Feijoa and blackberry showed the highest and strongest anti-inflammatory effects in the various test screens carried out for this research. The study also showed that the anti-oxidant action of the feijoa compounds was not a direct effect, but was mediated through inhibitory effects on the enzyme, kinase.

"Our studies support other results that suggest these fruit extracts could help to regulate oxidative stress and inflammation in cells, both directly and indirectly," says Professor Ferguson.

"Feijoa is already known to be very high in polyphenols such as flavonoids and these may be responsible for the anti-inflammatory effects. Research to identify the active compounds will be the subject of further studies," she says.

For the experiments reported in the study, the testing included the skin and pulp of all the fruits.

"In feijoa, the skin has more bio-activity than the pulp," says Professor Ferguson. "Some Asian cultures eat the skin, but in most western cultures many people find the taste too sour."

Explore further: Interleukin-27: Can a cytokine with both pro and anti-inflammatory activity make a good drug target?

Related Stories

Interleukin-27: Can a cytokine with both pro and anti-inflammatory activity make a good drug target?

October 20, 2014
Interleukin-27 (IL-27), a member of the interleukin family of cytokines that help regulate the immune system, has a mainly anti-inflammatory role in the body, and its dysfunction has been implicated in autoimmune diseases ...

Oxygen levels increase and decrease the effectiveness of anti-inflammatory therapies

December 2, 2013
A new research discovery published in the December 2013 issue of the Journal of Leukocyte Biology yields an important clue toward helping curb runaway inflammation. Oxygen levels play a critical role in determining the severity ...

Anti-epilepsy drugs can cause inflammations

December 19, 2013
Physicians at the Ruhr-Universität Bochum (RUB) have been investigating if established anti-epilepsy drugs have anti-inflammatory or pro-inflammatory properties – an effect for which these pharmaceutical agents are not ...

Working towards a worm protein pill for inflammatory disease

October 28, 2014
Australian scientists who have successfully regulated the inflammatory response in coeliac patients by infecting them with hookworms are now collaborating with a major pharmaceutical company to develop a treatment for inflammatory ...

Analgesics and anti-inflammatory drugs may have an impact on depression

October 21, 2014
Ordinary over the counter painkillers and anti-inflammatory drugs purchased from pharmacies may also be effective in the treatment of people suffering of depression.

Natural substance in red wine has an anti-inflammatory effect in cardiovascular diseases

December 4, 2014
A natural substance present in red wine, resveratrol, inhibits the formation of inflammatory factors that trigger cardiovascular diseases. This has been established by a research team at the Department of Pharmacology of ...

Recommended for you

The good and bad health news about your exercise posts on social media

February 22, 2018
We all have that Facebook friend—or 10—who regularly posts photos of his or her fitness pursuits: on the elliptical at the gym, hiking through the wilderness, crossing a 10K finish line.

Smartphones are bad for some teens, not all

February 21, 2018
Is the next generation better or worse off because of smartphones? The answer is complex and research shows it largely depends on their lives offline.

Lead and other toxic metals found in e-cigarette 'vapors': study

February 21, 2018
Significant amounts of toxic metals, including lead, leak from some e-cigarette heating coils and are present in the aerosols inhaled by users, according to a study from scientists at Johns Hopkins Bloomberg School of Public ...

Tackling health problems in the young is crucial for their children's future

February 21, 2018
A child's growth and development is affected by the health and lifestyles of their parents before pregnancy - even going back to adolescence - according to a new study by researchers at the Murdoch Children's Research Institute, ...

Why teens need up to 10 hours' sleep

February 21, 2018
Technology, other distractions and staying up late make is difficult, but researchers say teenagers need to make time for 8-10 hours of sleep a night to optimise their performance and maintain good health and wellbeing.

Electronic health records don't reduce administrative costs

February 21, 2018
The federal government thought that adopting certified electronic health record systems (EHR) would reduce administrative costs for physicians in a variety of specialties. However, a major new study conducted by researchers ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.