Herbal remedy derived from milk thistle demonstrates efficacy in non-alcoholic steatohepatitis

Results from a double-blind, placebo-controlled study of silymarin, which is derived from the milk thistle plant, have shown that this herbal remedy may be a useful treatment option for non-alcoholic steatohepatitis (NASH).

An interim analysis of the study, revealed today at The International Liver Congress 2015, shows a significantly higher percentage of patients experienced NASH resolution and improvement in fibrosis after 48 weeks of treatment with silymarin compared to placebo.

NASH occurs when the liver becomes inflamed due to the accumulation of fat. Over time, can lead to the formation of fibrous scar tissue in the liver and around its , which can eventually cause cirrhosis.

A total of 64 patients (silymarin = 30, placebo = 34) with biopsy-proven NASH had completed the study at the time of interim analysis. Silymarin has already demonstrated anti-oxidant, anti-inflammatory and anti-fibrotic properties, and these latest study results show that it may be a useful treatment for NASH.


Explore further

Liver injury in NASH leads to a leaky gut

Provided by European Association for the Study of the Liver
Citation: Herbal remedy derived from milk thistle demonstrates efficacy in non-alcoholic steatohepatitis (2015, April 23) retrieved 19 July 2019 from https://medicalxpress.com/news/2015-04-herbal-remedy-derived-thistle-efficacy.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
5 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more