Visit-to-visit SBP variability not linked to major cardiac events
Hiroyuki Arashi, M.D., from the Heart Institute of Japan in Tokyo, and colleagues examined the prognostic significance of visit-to-visit variability in systolic BP on subsequent MACE in patients with hypertension and CAD. A total of 2,049 patients were enrolled, and 1,734 patients had multiple follow-up visits (at least three) until their final follow-up.
The researchers found that the primary outcome of MACE occurred in 18.3 percent of patients during a median follow-up of 4.2 years. There was no correlation between visit-to-visit variability of systolic BP and the incidence of MACE. However, based on the mean systolic BP, the highest quartile for BP during follow-up correlated with subsequent MACE.
"In conclusion, in hypertensive patients with CAD, inadequate BP control is a strong predictor of subsequent MACE, whereas visit-to-visit variability of systolic BP is not," the authors write.
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