Male infertility might signal higher odds of testicular cancer

November 16, 2015
Male infertility might signal higher odds of testicular cancer
Abnormally low sperm count tied to greater risk, study suggests.

(HealthDay)—Men with reduced fertility could be at increased risk for testicular cancer, according to a new study.

Researchers looked at over 20,000 men who underwent semen analysis as part of between 1996 and 2011. They were compared to a control group with the same number of men known to be fertile.

Overall, 421 cases of cancer were diagnosed. The most common cancers were melanoma skin cancer, testicular and .

The subfertile men—those who sought infertility treatment—were three times more likely to develop than those in the , the study found. The risk was 10 times higher in those with an abnormally low sperm count.

Other types of sperm problems also increased the risk, the University of Utah researchers said in the Nov. 16 issue of the journal Fertility and Sterility.

However, the study doesn't establish a direct cause-and-effect relationship, so men with fertility problems shouldn't panic.

Contrary to previous studies, the researchers found no increased cancer risk in men with no sperm in their semen, they said in a journal news release.

Also, the investigators detected no link between fertility and .

"This study provides new insights that will help us deliver better patient care and provides a strong foundation for the research needed to identify, and ultimately address, underlying physiologic problems that may lead to infertility or cancer," Dr. Robert Oates, a past president of the Society for Male Reproduction and Urology, said in the news release.

Explore further: Men who have had testicular cancer are more likely to develop prostate cancer

More information: The U.S. National Cancer Institute has more about testicular cancer.

Related Stories

Men who have had testicular cancer are more likely to develop prostate cancer

February 24, 2015
A case-control study of close to 180,000 men suggests that the incidence of prostate cancer is higher among men with a history of testicular cancer (12.6 percent) than among those without a history of testicular cancer (2.8 ...

Risk of all cancers, specific cancers up in infertile men

May 5, 2015
(HealthDay)—Infertile men have increased risk of all cancers and some individual cancers, according to a study published in the May issue of The Journal of Urology.

Genetic testing could identify men at a 10-fold increased risk of testicular cancer

October 27, 2015
A new study of more than 25,000 men has uncovered four new genetic variants associated with increased risk of testicular cancer.

Men who can't produce sperm face increased cancer risk, study finds

June 21, 2013
Men who are diagnosed as azoospermic—infertile because of an absence of sperm in their ejaculate—are more prone to developing cancer than the general population, a study led by a Stanford University School of Medicine ...

Nearly half of testicular cancer risk comes from inherited genetic faults

September 9, 2015
Almost half of the risk of developing testicular cancer comes from the DNA passed down from our parents, a new study reports.

Recommended for you

Lab-grown 'mini tumours' could personalise cancer treatment

February 23, 2018
Testing cancer drugs on miniature replicas of a patient's tumour could help doctors tailor treatment, according to new research.

Study tracks evolutionary transition to destructive cancer

February 23, 2018
Evolution describes how all living forms cope with challenges in their environment, as they struggle to persevere against formidable odds. Mutation and selective pressure—cornerstones of Darwin's theory—are the means ...

Researchers use a molecular Trojan horse to deliver chemotherapeutic drug to cancer cells

February 23, 2018
A research team at the University of California, Riverside has discovered a way for chemotherapy drug paclitaxel to target migrating, or circulating, cancer cells, which are responsible for the development of tumor metastases.

An under-the-radar immune cell shows potential in fight against cancer

February 23, 2018
One of the rarest of immune cells, unknown to scientists a decade ago, might prove to be a potent weapon in stopping cancer from spreading in the body, according to new research from the University of British Columbia.

Putting black skin cancer to sleep—for good

February 22, 2018
An international research team has succeeded in stopping the growth of malignant melanoma by reactivating a protective mechanism that prevents tumor cells from dividing. The team used chemical agents to block the enzymes ...

Cancer risk associated with key epigenetic changes occurring through normal aging process

February 22, 2018
Some scientists have hypothesized that tumor-promoting changes in cells during cancer development—particularly an epigenetic change involving DNA methylation—arise from rogue cells escaping a natural cell deterioration ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.