Cannabis indica. Credit: Wikipedia

Cannabis dependence is a serious problem worldwide and it is of growing importance in the United States as marijuana becomes increasingly legal.

A new study published online by JAMA Psychiatry examined what specific genetic variants might contribute to .

Joel Gelernter, M.D., of the Yale School of Medicine, New Haven, Conn., and coauthors conducted a genome-wide association study for DSM-IV cannabis dependence criterion in three independent substance dependence study groups among African American and European American participants.

The authors report cannabis dependence has a genetic risk component that may overlap with other psychiatric disorders.

More information: JAMA Psychiatry. Published online March 30, 2016. DOI: 10.1001/jamapsychiatry.2016.0036

Journal information: JAMA Psychiatry