Systolic blood pressure variability linked to mortality, morbidity

September 29, 2016

(HealthDay)—Systolic blood pressure variability (SBPV) is associated with mortality, coronary heart disease (CHD), stroke, and end-stage renal disease (ESRD), according to a study published in the Sept. 27 issue of the Journal of the American College of Cardiology.

Elvira O. Gosmanova, M.D., from the Stratton Veterans Affairs Medical Center in Albany, N.Y., and colleagues examined the impact of increased visit-to-visit variability in a large cohort of U.S. veterans. Data were included for 2,865,157 patients with eight or more outpatient BP measurements. SBPV was measured and correlated with all-cause mortality, incident CHD, stroke, and ESRD.

The researchers found that higher intraindividual SBPV was seen in association with sociodemographic variables (older age, male sex, African-American race, divorced or widowed status), clinical characteristics (lower baseline estimated , higher SBP, and diastolic BP), and comorbidities (presence of diabetes, hypertension, cardiovascular disease, and lung disease). For standard deviation quartile 2 through 4 versus the first quartile, the multivariable-adjusted hazard ratios associated with all-cause mortality, CHD, stroke, and ESRD were incrementally higher.

"Higher SBPV in individuals with and without hypertension was associated with increased risks of all-cause mortality, CHD, stroke, and ESRD," the authors write. "Further studies are needed to determine interventions that can lower SBPV and their impact on adverse health outcomes."

Explore further: Ideal BP in elderly with chronic kidney disease unclear

More information: Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Related Stories

Ideal BP in elderly with chronic kidney disease unclear

April 22, 2016

(HealthDay)—Age modifies the association between blood pressure (BP) and adverse cardiovascular and renal outcomes in elderly patients with chronic kidney disease (CKD), according to research published online April 21 in ...

Decline in eGFR mainly linear in type 1 diabetes

September 22, 2016

(HealthDay)—For patients with type 1 diabetes, the decline of estimated glomerular filtration rate (eGFR) is mainly linear, according to a study published online Sept. 19 in Diabetes Care.

Depression linked to CKD in patients with diabetes

July 13, 2016

(HealthDay)—For patients with diabetes, the presence of depression is associated with increased risk of developing chronic kidney disease (CKD), according to a study published online June 16 in Diabetes Care.

Review finds CABG bests PCI in end-stage renal disease

May 5, 2016

(HealthDay)—For patients with end-stage renal disease (ESRD) referred for coronary revascularization, coronary artery bypass grafting (CABG) is associated with a small decrease in long-term mortality compared with percutaneous ...

Recommended for you

Hypertension in young adults shows long-term heart risks

May 19, 2017

Otherwise healthy young people with high systolic blood pressure over 140 are at greater risk for future artery stiffening linked to an increased risk of stroke as well as possible damage to the kidneys and brain, new research ...

Team discovers way to help heart failure patients

May 17, 2017

Shortness of breath is the No.1 complaint of people suffering from heart failure. Now a University of Guelph researcher has discovered its surprising cause - and an effective treatment - in a groundbreaking new study.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.