Noncardiovascular cause of death more common in CHD patients

December 19, 2016

(HealthDay)—For patients with coronary heart disease (CHD), mortality is more often due to noncardiovascular causes, according to a study published in the Jan. 1 issue of The American Journal of Cardiology.

Elizabeth Y. Wang, from the University of California in San Francisco, and colleagues determined the proportion of patients with CHD who died from cardiovascular versus noncardiovascular causes and the causes and predictors of death. A total of 1,024 participants from the Heart and Soul Study with stable CHD were enrolled from 2000 to 2002 and followed for 10 years.

The researchers found that 401 participants died during 7,680 person-years of follow-up. Of these deaths, 42.4 and 54.4 percent, respectively, were cardiovascular and noncardiovascular. Seventy-two percent of cardiovascular deaths were accounted for by myocardial infarction, stroke, and sudden death. Sixty-seven percent of noncardiovascular deaths were accounted for by cancer, pneumonia, and sepsis. Older age, inducible ischemia on stress echocardiography, higher heart rate at rest, smoking, lower hemoglobin, and higher N-terminal pro-brain natriuretic peptide were independent predictors of (all P < 0.05). Older age, inducible ischemia, higher heart rate, lower exercise capacity, and nonuse of statins were independent predictors of noncardiac (all P < 0.05).

"In conclusion, mortality in this cohort was more frequently due to noncardiovascular causes, and predictors of noncardiovascular mortality included factors traditionally associated with ," the authors write.

Explore further: Diabetes linked to increased CVD, cancer, other mortality

More information: Full Text (subscription or payment may be required)

Related Stories

Diabetes linked to increased CVD, cancer, other mortality

August 19, 2016
(HealthDay)—Diabetes is associated with increased mortality from cardiovascular disease, cancer, and noncardiovascular noncancer causes, according to a study published online Aug. 4 in Diabetes Care.

Unrecognized MI tied to higher noncardiovascular mortality risk

January 7, 2014
(HealthDay)—Unrecognized myocardial infarction (MI) is associated with long-term increased risks of cardiovascular and noncardiovascular mortality, according to a study published in the Jan. 1 issue of The American Journal ...

Higher resting heart rate linked to increased risk of death from all causes

November 23, 2015
A higher resting heart rate is associated with an increased risk of death from all causes in the general population, even in people without the usual risk factors for heart disease, according to new research published in ...

Does 'good' cholesterol matter in heart disease risk?

October 31, 2016
(HealthDay)—A large new study adds to questions about whether your "good" HDL cholesterol levels really affect your risk of heart disease.

CDC: Heart failure mortality up 2012 through 2014

January 4, 2016
(HealthDay)—The age-adjusted mortality rates from heart failure decreased from 2000 to 2012 but increased from 2012 through 2014, according to a December data brief published by the U.S. Centers for Disease Control and ...

Recommended for you

Can stem cells help a diseased heart heal itself? Researchers achieve important milestone

December 14, 2018
A team of Rutgers scientists, including Leonard Lee and Shaohua Li, have taken an important step toward the goal of making diseased hearts heal themselves—a new model that would reduce the need for bypass surgery, heart ...

Your weight history may predict your heart failure risk

December 12, 2018
In a medical records analysis of information gathered on more than 6,000 people, Johns Hopkins Medicine researchers conclude that simply asking older adult patients about their weight history at ages 20 and 40 could provide ...

New understanding of mysterious 'hereditary swelling'

December 12, 2018
For the first time ever, biomedical researchers from Aarhus University, Denmark, report cellular defects that lead to a rare disease, hereditary angioedema (HAE), in which patients experience recurrent episodes of swelling ...

Age is the biggest risk for heart disease, but lifestyle and meds have impact

December 12, 2018
Of all the risk factors for heart disease, age is the strongest predictor of potential trouble.

Higher risk of heart attack on Christmas Eve

December 12, 2018
The risk of heart attack peaks at around 10pm on Christmas Eve, particularly for older and sicker people, most likely due to heightened emotional stress, finds a Swedish study in this week's Christmas issue of The BMJ.

Researchers have found that incidence of heart failure was around two-fold higher in people with diabetes

December 11, 2018
Researchers have found that incidence of heart failure was around two-fold higher in people with diabetes.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.