Platelet-rich plasma superior for lumbar facet joint syndrome

December 28, 2016

(HealthDay)—For intra-articular injection autologous platelet-rich plasma (PRP) and local anesthetic (LA)/corticosteroid are effective, easy, and safe in the treatment of lumbar facet joint syndrome, according to a study published online Dec. 18 in Pain Practice.

Jiuping Wu, from Jilin University in Changchun, China, and colleagues randomized 46 patients with lumbar facet joint syndrome into group A (intra-articular injection with PRP) and group B (intra-articular injection with LA/corticosteroid). Outcome assessments were performed immediately after and at one week, one month, two months, three months, and six months after .

The researchers found that, compared with pretreatment, both group A and group B demonstrated statistical improvements in the visual analogue scale score at rest or during flexion, the Roland-Morris Disability Questionnaire, and the Oswestry Disability Index (P < 0.01). There were also significant differences between the groups for these measures (P < 0.05). Based on the modified MacNab criteria for pain relief, for group B, subjective satisfaction criteria and objective success rate were highest (80 and 85 percent, respectively) after one month, but only 50 and 20 percent, respectively, after six months. For group A, however, the measures increased over time.

"Both autologous PRP and LA/corticosteroid for intra-articular are effective, easy, and safe enough in the treatment of lumbar facet joint syndrome," the authors write. "However, autologous PRP is a superior treatment option for longer duration efficacy."

Explore further: Intra-articular, systemic steroids beneficial in back pain

More information: Full Text (subscription or payment may be required)

Related Stories

Intra-articular, systemic steroids beneficial in back pain

November 7, 2013
(HealthDay)—Intra-articular injection of steroids is slightly better than intramuscular injection for the treatment of facet joint syndrome, although both are effective, according to a study published in the Nov. 1 issue ...

Platelet-rich plasma SIJ injection cuts low back pain

October 3, 2016
(HealthDay)—For patients with chronic low back pain, ultrasound-guided sacroiliac joint (SIJ) injection with platelet-rich plasma (PRP) is effective for reducing pain, according to a study published online Sept. 27 in Pain ...

Radiofrequency neurotomy efficient in knee osteoarthritis

August 23, 2016
(HealthDay)—For patients with chronic knee osteoarthritis (OA) pain, radiofrequency (RF) neurotomy of genicular nerves is safe and efficient, according to a study published online Aug. 12 in the International Journal of ...

Autologous adipose-derived stromal cells may ease knee OA

June 27, 2016
(HealthDay)—For patients with knee osteoarthritis, a single intra-articular injection of autologous adipose-derived stromal cells (ASCs) can reduce pain and inflammation, according to research published online May 23 in ...

AAPM: Platelet-rich plasma offers short-term benefit

March 31, 2015
(HealthDay)—For patients with facet joint arthropathy, platelet-rich plasma (PRP) has a short-term positive impact, according to a study presented at the annual meeting of the American Academy of Pain Medicine, held from ...

Wnt inhibitor may ease pain, and improve function and cartilage loss in knee OA

November 13, 2016
Injection of a Wnt inhibitor drug showed promise to ease pain, improve joint function, and even slow or reverse cartilage loss in patients with knee osteoarthritis, according to new research findings presented this week at ...

Recommended for you

Pair of discoveries illuminate new paths to flu and anthrax treatments

October 17, 2017
Two recent studies led by biologists at the University of California San Diego have set the research groundwork for new avenues to treat influenza and anthrax poisoning.

Portable 3-D scanner assesses patients with elephantiasis

October 17, 2017
An estimated 120 million people worldwide are infected with lymphatic filariasis, a parasitic, mosquito-borne disease that can cause major swelling and deformity of the legs, a condition known as elephantiasis. Health-care ...

New tools to combat kidney fibrosis

October 16, 2017
Interstitial fibrosis – excessive tissue scarring – contributes to chronic kidney disease, which is increasing in prevalence in the United States.

How hepatitis C hides in the body

October 13, 2017
The Hepatitis C (HCV) virus is a sly enemy to have in one's body. Not only does it manage to make itself invisible to the immune system by breaking down communication between the immune cells, it also builds secret virus ...

Largest study yet of malaria in Africa shows historical rates of infection

October 12, 2017
(Medical Xpress)—A team of researchers with members from the Kenya Medical Research Institute, the University of Oxford and the University of KwaZulu-Natal has conducted the largest-ever study of the history of malaria ...

Promising new target for treatment of psoriasis is safe, study shows

October 11, 2017
A protein known to play a significant role in the development of psoriasis can be prevented from functioning without posing a risk to patients, scientists at King's College London have found.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.