Platelet-rich plasma superior for lumbar facet joint syndrome

December 28, 2016

(HealthDay)—For intra-articular injection autologous platelet-rich plasma (PRP) and local anesthetic (LA)/corticosteroid are effective, easy, and safe in the treatment of lumbar facet joint syndrome, according to a study published online Dec. 18 in Pain Practice.

Jiuping Wu, from Jilin University in Changchun, China, and colleagues randomized 46 patients with lumbar facet joint syndrome into group A (intra-articular injection with PRP) and group B (intra-articular injection with LA/corticosteroid). Outcome assessments were performed immediately after and at one week, one month, two months, three months, and six months after .

The researchers found that, compared with pretreatment, both group A and group B demonstrated statistical improvements in the visual analogue scale score at rest or during flexion, the Roland-Morris Disability Questionnaire, and the Oswestry Disability Index (P < 0.01). There were also significant differences between the groups for these measures (P < 0.05). Based on the modified MacNab criteria for pain relief, for group B, subjective satisfaction criteria and objective success rate were highest (80 and 85 percent, respectively) after one month, but only 50 and 20 percent, respectively, after six months. For group A, however, the measures increased over time.

"Both autologous PRP and LA/corticosteroid for intra-articular are effective, easy, and safe enough in the treatment of lumbar facet joint syndrome," the authors write. "However, autologous PRP is a superior treatment option for longer duration efficacy."

Explore further: Intra-articular, systemic steroids beneficial in back pain

More information: Full Text (subscription or payment may be required)

Related Stories

Intra-articular, systemic steroids beneficial in back pain

November 7, 2013
(HealthDay)—Intra-articular injection of steroids is slightly better than intramuscular injection for the treatment of facet joint syndrome, although both are effective, according to a study published in the Nov. 1 issue ...

Platelet-rich plasma SIJ injection cuts low back pain

October 3, 2016
(HealthDay)—For patients with chronic low back pain, ultrasound-guided sacroiliac joint (SIJ) injection with platelet-rich plasma (PRP) is effective for reducing pain, according to a study published online Sept. 27 in Pain ...

Radiofrequency neurotomy efficient in knee osteoarthritis

August 23, 2016
(HealthDay)—For patients with chronic knee osteoarthritis (OA) pain, radiofrequency (RF) neurotomy of genicular nerves is safe and efficient, according to a study published online Aug. 12 in the International Journal of ...

Autologous adipose-derived stromal cells may ease knee OA

June 27, 2016
(HealthDay)—For patients with knee osteoarthritis, a single intra-articular injection of autologous adipose-derived stromal cells (ASCs) can reduce pain and inflammation, according to research published online May 23 in ...

AAPM: Platelet-rich plasma offers short-term benefit

March 31, 2015
(HealthDay)—For patients with facet joint arthropathy, platelet-rich plasma (PRP) has a short-term positive impact, according to a study presented at the annual meeting of the American Academy of Pain Medicine, held from ...

Wnt inhibitor may ease pain, and improve function and cartilage loss in knee OA

November 13, 2016
Injection of a Wnt inhibitor drug showed promise to ease pain, improve joint function, and even slow or reverse cartilage loss in patients with knee osteoarthritis, according to new research findings presented this week at ...

Recommended for you

First proof a synthesized antibiotic is capable of treating superbugs

March 23, 2018
A "game changing" new antibiotic which is capable of killing superbugs has been successfully synthesised and used to treat an infection for the first time—and could lead to the first new class of antibiotic drug in 30 years.

Scientists identify potential drug target in blood-feeding hookworms

March 22, 2018
In hookworms that infect and feed on the blood of mice, scientists have discovered a key step in blood digestion that can be targeted to disrupt the parasite's development and survival. These findings, published in PLOS Pathogens ...

Global burden of low back pain—a consequence of negligence and misinformation

March 21, 2018
A series of groundbreaking papers from Australian and international researchers in The Lancet, published today (22/3) warns that low back pain is a major health burden globally - across developed and developing nations - ...

Microscopic 'shuttles' transport enzyme from cells to trigger onset of kidney disease

March 21, 2018
A new study involving the University of Sheffield has identified a key culprit in the onset of kidney disease in a major marker for kidney disease development.

Metabolite therapy proves effective in treating C. difficile in mice

March 20, 2018
A team of UCLA researchers found that a metabolite therapy was effective in mice for treating a serious infection of the colon known as Clostridium difficile infection, or C. difficile.

Study of COPD patients has created a 'looking glass' into genome of pathogen

March 19, 2018
Decades of work on chronic obstructive pulmonary disease (COPD) at the University at Buffalo and the Veterans Affairs Western New York Healthcare System have yielded extraordinary information about the pathogen that does ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.