Prevalence of anti-TSH receptor antibody high in fibromyalgia

December 12, 2016

(HealthDay)—Patients with fibromyalgia syndrome (FMS) have high prevalence of anti-thyroid-stimulating hormone (TSH) receptor antibody (TRAb), according to a study published online Nov. 30 in the International Journal of Rheumatic Diseases.

Kenya Nishioka, M.D., Ph.D., from the Juntendo University Graduate School of Medicine in Tokyo, and colleagues tested for titers of free tri-iodothyronine, free thyroxine, TSH, anti-thyroid peroxidase antibody (TPOAb), anti-thyroglobulin antibody (TgAb), and TRAb in 207 with FMS. Twenty-five patients with subclinical hyper- or hypothyroidism, or overt hypothyroidism were excluded.

The researchers identified 69 patients with autoimmune thyroid diseases (AITD; 37.9 percent). The prevalence of positivity for TRAb was 20.3 percent, TgAb was 16.5 percent, and TPOAb was 13.2 percent. The prevalence of TRAb positivity was high compared to control populations in previous studies, and TRAb titers were low. Compared with previous studies reporting on FMS patients, the prevalence of TPOAb and TgAb positivity were not significantly higher. Identical clinical symptom profiles were seen for FMS patients with and without AITD.

"We found a high prevalence of AITD among 207 patients with clinically defined FMS, with TRAb being especially prominent among these patients," the authors write. "Further study is needed to evaluate changes in thyroid function among FMS patients with AITD."

Explore further: Prevalence, risk of thyroid disease up in vitiligo patients

More information: Full Text (subscription or payment may be required)

Related Stories

Prevalence, risk of thyroid disease up in vitiligo patients

August 13, 2012
(HealthDay) -- Both the prevalence and the risk of thyroid diseases are significantly higher among patients with vitiligo compared to those without the condition, according to a study published online Aug. 3 in the British ...

Anti-TNF treatment ups ANA positivity in psoriasis

December 23, 2015
(HealthDay)—For patients with psoriasis, treatment with anti-tumor necrosis factor (TNF) agents is associated with increased rates of antinuclear antibody (ANA) positivity, according to a letter to the editor published ...

Thyroid health important to all, says expert

September 15, 2016
Thyroid problems are five to eight times more likely to impact women than men. However, Baylor College of Medicine's Dr. Ruchi Gaba cautions that any person, regardless of gender or age, can be affected by thyroid issues.

Subclinical hypothyroidism may not up VTE recurrence risk

February 8, 2016
(HealthDay)—In the elderly, subclinical hypothyroidism is not associated with significantly increased risk of recurrent venous thromboembolism (rVTE), according to research published online Jan. 27 in the Journal of Thrombosis ...

More diabetes-associated, non-associated autoantibodies in T1D

September 6, 2016
(HealthDay)—Patients with type 1 diabetes have more diabetes-associated autoantibodies (DAAs) and non-DAAs than patients with type 2 diabetes, according to a study published online Aug. 29 in Diabetes Care.

Study finds few patients with newly-diagnosed hyperlipidemia receive recommended thyroid screening

November 13, 2013
Despite current guidelines that recommend newly diagnosed high-cholesterol patients have a TSH blood test done to make sure they do not have hypothyroidism, researchers from Boston University School of Medicine (BUSM) and ...

Recommended for you

Osteoarthritis could be treated as two diseases, scientists reveal

January 10, 2018
Scientists at The University of Manchester have discovered that most people with osteoarthritis can be subdivided into two distinct disease groups, with implications for diagnosis and drug development.

US arthritis prevalence is much higher than current estimates

November 27, 2017
New research indicates that the prevalence of arthritis in the United States has been substantially underestimated, especially among adults

Maintaining sufficient vitamin D levels may help to prevent rheumatoid arthritis

November 20, 2017
Maintaining sufficient vitamin D levels may help to prevent the onset of inflammatory diseases like rheumatoid arthritis, research led by the University of Birmingham has discovered.

Old World monkeys could be key to a new, powerful rheumatoid arthritis therapy

November 16, 2017
In the quest for a new and more effective treatment for rheumatoid arthritis, researchers from the Keck School of Medicine of USC looked to a primate that mostly roams the land in Asia, the Middle East and Africa. It was ...

Study lists foods for fighting rheumatoid arthritis symptoms and progression

November 8, 2017
A list of food items with proven beneficial effects on the progression and symptoms of rheumatoid arthritis is provided in a new study published today in Frontiers in Nutrition. The authors suggest incorporating these foods ...

Prototype equipment can detect rheumatoid arthritis

September 28, 2017
According to a first clinical study published in the scientific journal Photoacoustics, the University of Twente and various European partners have designed a device that shows the difference between healthy fingers and arthritic ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.