Ultrasound IDs disease activity in rheumatoid arthritis

February 15, 2017

(HealthDay)—A 12-joint ultrasound (US) evaluation is relevant in determining disease activity in rheumatoid arthritis patients, according to a study published online Feb. 9 in the International Journal of Rheumatic Diseases.

Marcos Cerqueira, M.D., from the Hospital Conde de Bertiandos in Ponte de Lima, Portugal, and colleagues performed a 12-joint US assessment on the same day as a routine clinical assessment in 41 with on biological disease-modifying antirheumatic drug treatment.

The researchers found Grey-scale and Power Doppler >0 in 24 and 3 percent of the ankles, 21 and 17 percent of the wrists, 19 and 9 percent of the second metacarpophalangeal joints (MCP), 7 and 2 percent of the third MCP, 6 and 0 percent of the knees, and 5 and 0 percent of the elbows, respectively. Nineteen percent of the ankles had tenosynovitis of the tibialis posterior. A US score of 0 was seen in eight of the 15 patients with Disease Activity Score of 28 joints ≤2.6. Overall, 6.7 percent of joints had US evidence of synovitis but were not swollen and 2.5 percent were swollen with no US evidence of synovitis.

"A regular and standardized US assessment of RA patients is therefore warranted to complement clinical evaluation and better define ," the authors write.

Explore further: Active synovitis with osteitis predicts residual synovitis in RA

More information: Full Text (subscription or payment may be required)

Related Stories

Active synovitis with osteitis predicts residual synovitis in RA

February 8, 2017
(HealthDay)—For patients with rheumatoid arthritis (RA) who have clinical response to treatment, active synovitis with osteitis is associated with subsequent residual synovitis (R-synovitis), according to a study published ...

Ultrasound model IDs residual joint inflammation in RA

April 18, 2013
(HealthDay)—A model including ultrasound (US) assessment of the wrist, metacarpophalangeal (MCP), ankle, and metatarsophalangeal (MTP) joints is highly sensitive for detecting B-mode and Doppler joint inflammation in patients ...

Ultrasound findings can improve classification of RA

May 15, 2013
(HealthDay)—Compared to clinical diagnosis of synovitis, ultrasound-detected synovitis provides either improved sensitivity or specificity when used with the American College of Rheumatology/European League Against Rheumatism ...

Non-TNF biologic beats second anti-TNF in rheumatoid arthritis

September 21, 2016
(HealthDay)—A non-tumor necrosis factor (TNF)-targeted biologic is more effective than a second anti-TNF drug for treatment of rheumatoid arthritis in patients with insufficient response to a first anti-TNF drug, according ...

Short-course tocilizumab may up hep B reactivation in RA

February 13, 2017
(HealthDay)—For patients with rheumatoid arthritis (RA), one to three doses of tocilizumab may increase the risk of hepatitis B virus (HBV) reactivation, according to a study published online Feb. 3 in the International ...

Ultrasound-defined tenosynovitis identified as strong predictor of early RA

June 10, 2015
The results of a study presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) Press Conference showed that ultrasound diagnosis of tenosynovitis (inflammation of the tendon sheath) was superior ...

Recommended for you

Scientists find key proteins control risk of osteoarthritis during aging

February 14, 2018
More than 30 million Americans suffer from osteoarthritis making it one of the most common age-related diseases.

Acute treatment suppresses posttraumatic arthritis in ankle injury

February 7, 2018
A University of Iowa study has identified a method for inhibiting the occurrence of an aggressive form of arthritis that frequently develops following a severe traumatic injury. The preclinical work demonstrates the potential ...

Small molecule could make a big difference for arthritis patients

February 7, 2018
Will there come a time when a patient with arthritis can forgo joint replacement surgery in favor of a shot? Keck School of Medicine of USC scientist Denis Evseenko, MD, PhD, has reason to be optimistic.

Study finds bacteria in milk linked to rheumatoid arthritis

January 30, 2018
A strain of bacteria commonly found in milk and beef may be a trigger for developing rheumatoid arthritis in people who are genetically at risk, according to a new study from the University of Central Florida.

Osteoarthritis could be treated as two diseases, scientists reveal

January 10, 2018
Scientists at The University of Manchester have discovered that most people with osteoarthritis can be subdivided into two distinct disease groups, with implications for diagnosis and drug development.

US arthritis prevalence is much higher than current estimates

November 27, 2017
New research indicates that the prevalence of arthritis in the United States has been substantially underestimated, especially among adults

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.