Does boosting 'good' cholesterol really improve your health?

cholesterol
Space-filling model of the Cholesterol molecule. Credit: RedAndr/Wikipedia

A new review addresses the mysteries behind "good" HDL cholesterol and why boosting its levels does not necessarily provide protection from cardiovascular risk for patients. It appears that augmenting the function of HDL cholesterol, rather than its concentration, is key.

The review details the manner in which tissue and affects the metabolism of HDL cholesterol via several pathways, pointing to ways to improve its production and function.

"Our own clinical studies as well as in vitro and animal studies performed by other groups have demonstrated the significance of adipose, or fat, tissue for optimal HDL cholesterol metabolism and function. Currently, it is accepted that adipose tissue inflammation is one of the hallmarks of systemic inflammation, thus, it is our hypothesis that addressing adipose tissue-associated systemic inflammation will support the atheroprotective role of HDL," said Dr. Demidmaa Tuvdendorj, senior author of the British Journal of Pharmacology article.


Explore further

Bariatric surgery improves adipose tissue function

More information: British Journal of Pharmacology, DOI: 10.1111/bph.13743
Journal information: British Journal of Pharmacology

Provided by Wiley
Citation: Does boosting 'good' cholesterol really improve your health? (2017, March 22) retrieved 19 August 2019 from https://medicalxpress.com/news/2017-03-boosting-good-cholesterol-health.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
0 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more