Examining whether migraine is associated with cervical artery dissection

March 6, 2017, The JAMA Network Journals
Credit: Sasha Wolff/Wikipedia

A new study published online by JAMA Neurology examines whether a history of migraine is associated with cervical artery dissection (CEAD), a frequent cause of ischemic (blood vessel-related) stroke in young and middle-age adults, although the causes leading to vessel damage are unclear.

The study by Alessandro Pezzini, M.D., of the Universitá degli Studi di Brescia, Italy, and coauthors included 2,485 patients (ages 18 to 45) with their first from one of the largest registries of patients with early-onset ischemic .

Of the 2,485 patients included in the registry, 334 (13.4 percent) had CEAD ischemic stroke and 2,151 (86.6 percent) had non-CEAD ischemic stroke.

Patients with non-CEAD ischemic stroke were more likely to have an unfavorable cardiovascular risk factor profile, including diabetes, high cholesterol and current smoking. Migraine was more common in the group of patients with CEAD ischemic stroke, mainly because of the frequency of without aura, according to the results.

Compared with migraine with aura, migraine without aura was associated with CEAD ischemic stroke and that association was higher in men and in patients 39 and younger, the article reports.

The study has limitations, including that it did not assess migraine frequency and severity or the frequency of auras, so the authors could not evaluate whether the association they observed differs according to specific migraine patterns.

"Our data support consideration of a history of migraine as a marker for increased risk of IS [ischemic stroke] caused by CEAD, as well as a putative susceptibility factor for CEAD, regardless of its clinical features," the article concludes.

Explore further: Migraine associated with higher risk of stroke after surgery

More information: JAMA Neurol. Published online March 6, 2017. DOI: 10.1001/jamaneurol.2016.5704

Related Stories

Migraine associated with higher risk of stroke after surgery

January 10, 2017
Surgical patients with a history of migraines have a greater risk of stroke and readmission to hospital, finds a study published by The BMJ today.

Migraine with aura linked to clot-caused strokes

February 17, 2016
People who have migraines with aura are more likely to have strokes caused by either a blood clot in the heart (cardio-embolic stroke) or a clot within the brain's blood vessels (thrombotic stroke), compared to those that ...

Headache far more common stroke symptom in children than adults

February 22, 2017
Children are far more likely than adults to report headache when having a stroke, according to research presented at the American Stroke Association's International Stroke Conference 2017.

People who suffer migraine headaches may be at double the risk of stroke

March 25, 2015
People who suffer migraine headaches with auras are at roughly double the risk of suffering the most common type of stroke.

Recommended for you

A nanoparticle inhalant for treating heart disease

January 18, 2018
A team of researchers from Italy and Germany has developed a nanoparticle inhalant for treating people suffering from heart disease. In their paper published in the journal Science Translational Medicine, the group describes ...

Starting periods before age of 12 linked to heightened risk of heart disease and stroke

January 15, 2018
Starting periods early—before the age of 12—is linked to a heightened risk of heart disease and stroke in later life, suggests an analysis of data from the UK Biobank study, published online in the journal Heart.

'Decorated' stem cells could offer targeted heart repair

January 10, 2018
Although cardiac stem cell therapy is a promising treatment for heart attack patients, directing the cells to the site of an injury - and getting them to stay there - remains challenging. In a new pilot study using an animal ...

Two simple tests could help to pinpoint cause of stroke

January 10, 2018
Detecting the cause of the deadliest form of stroke could be improved by a simple blood test added alongside a routine brain scan, research suggests.

Exercise is good for the heart, high blood pressure is bad—researchers find out why

January 10, 2018
When the heart is put under stress during exercise, it is considered healthy. Yet stress due to high blood pressure is bad for the heart. Why? And is this always the case? Researchers of the German Centre for Cardiovascular ...

Heart-muscle patches made with human cells improve heart attack recovery

January 10, 2018
Large, human cardiac-muscle patches created in the lab have been tested, for the first time, on large animals in a heart attack model. This clinically relevant approach showed that the patches significantly improved recovery ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.