Examining whether migraine is associated with cervical artery dissection

Migraine
Credit: Sasha Wolff/Wikipedia

A new study published online by JAMA Neurology examines whether a history of migraine is associated with cervical artery dissection (CEAD), a frequent cause of ischemic (blood vessel-related) stroke in young and middle-age adults, although the causes leading to vessel damage are unclear.

The study by Alessandro Pezzini, M.D., of the Universit√° degli Studi di Brescia, Italy, and coauthors included 2,485 patients (ages 18 to 45) with their first from one of the largest registries of patients with early-onset ischemic .

Of the 2,485 patients included in the registry, 334 (13.4 percent) had CEAD ischemic stroke and 2,151 (86.6 percent) had non-CEAD ischemic stroke.

Patients with non-CEAD ischemic stroke were more likely to have an unfavorable cardiovascular risk factor profile, including diabetes, high cholesterol and current smoking. Migraine was more common in the group of patients with CEAD ischemic stroke, mainly because of the frequency of without aura, according to the results.

Compared with migraine with aura, migraine without aura was associated with CEAD ischemic stroke and that association was higher in men and in patients 39 and younger, the article reports.

The study has limitations, including that it did not assess migraine frequency and severity or the frequency of auras, so the authors could not evaluate whether the association they observed differs according to specific migraine patterns.

"Our data support consideration of a history of migraine as a marker for increased risk of IS [ischemic stroke] caused by CEAD, as well as a putative susceptibility factor for CEAD, regardless of its clinical features," the article concludes.


Explore further

Migraine associated with higher risk of stroke after surgery

More information: JAMA Neurol. Published online March 6, 2017. DOI: 10.1001/jamaneurol.2016.5704
Journal information: Archives of Neurology

Citation: Examining whether migraine is associated with cervical artery dissection (2017, March 6) retrieved 20 October 2019 from https://medicalxpress.com/news/2017-03-migraine-cervical-artery.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
0 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more