Dizziness inPparkinson's may be due to cerebral hypoperfusion

April 17, 2017

(HealthDay)—Cerebral hypoperfusion contributes to dizziness in patients with Parkinson's disease (PD), even without orthostatic hypotension (OH), according to a study published online April 12 in the Journal of Clinical Ultrasound.

Jinse Park, M.D., from Inje University in Busan, South Korea, and colleagues conducted transcranial Doppler and blood pressure monitoring for 10 minutes during the head-up tilt test in PD patients with dizziness and OH (22 patients; group 1), PD patients with dizziness but no OH (23; group 2), PD patients without dizziness (11; group 3), and age-matched healthy controls (10; group 4).

The researchers found that group 1 showed a significantly higher change in mean blood pressure within three minutes after head-up tilting, compared to the other groups (P < 0.001). However, groups 3 and 4 showed a significantly smaller change in cerebral blood flow velocity in the than groups 1 and 2 (P < 0.01).

"Transcranial Doppler monitoring during head-up tilting may be a useful tool for evaluating in PD patients with or without OH," the authors write.

Explore further: Reduction in dizziness, not falls, after routine cataract surgery

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Reduction in dizziness, not falls, after routine cataract surgery

November 12, 2015
(HealthDay)—Cataract surgery is associated with a reduction in the number of patients with dizziness, but not with a decrease in falls, according to a study published online Nov. 9 in Ophthalmic & Physiological Optics.

Rapid blood pressure drops in middle age linked to dementia in old age

March 10, 2017
Middle-aged people who experience temporary blood pressure drops that often cause dizziness upon standing up may be at an increased risk of developing cognitive decline and dementia 20 years later, new Johns Hopkins Bloomberg ...

Traumatic brain injury complications common among US combat soldiers

February 6, 2013
U.S. soldiers in combat often suffer constricted blood vessels and increased pressure in the brain—significant complications of traumatic brain injuries, according to research presented at the American Stroke Association's ...

Is head CT overused in emergency departments?

January 26, 2015
Less than 7.1% of patients presenting to the emergency department with dizziness and 6.4% complaining of syncope or near-syncope benefited from head CT say researchers at Kaiser Foundation Hospital in Honolulu. The use of ...

Sudden blood pressure drops associated with long-term dementia risk

October 11, 2016
Orthostatic hypotension—low blood pressure when suddenly standing up—is associated with a 15 percent increase in a person's long-term risk of dementia, including Alzheimer's disease, according to a twenty-four year study ...

Coronary angiography, PCI don't impact cognitive function

November 8, 2016
(HealthDay)—There is no indication of postprocedural cognitive impairment for patients undergoing coronary angiography (CA) or percutaneous coronary intervention (PCI), according to a study published in the Nov. 15 issue ...

Recommended for you

Protein levels in spinal fluid correlate to posture and gait difficulty in Parkinson's

February 21, 2018
Levels of a protein found in the brain called alpha-synuclein (α-syn) are significantly lower than normal in cerebrospinal fluid collected in Parkinson's disease patients suffering from postural instability and gait difficulty, ...

Calcium may play a role in the development of Parkinson's disease

February 19, 2018
Researchers have found that excess levels of calcium in brain cells may lead to the formation of toxic clusters that are the hallmark of Parkinson's disease.

New method maps the dopamine system in Parkinson's patients

February 14, 2018
With the aid of a PET camera, researchers from Karolinska Institutet in Sweden have developed a new method for investigating the dopamine system in the brains of patients suffering from Parkinson's disease. The method measures ...

Mechanism behind common Parkinson's mutation discovered

February 5, 2018
Northwestern Medicine investigators have discovered how a gene mutation results in buildup of a toxic compound known to cause Parkinson's disease symptoms, defining for the first time the mechanism underlying that aspect ...

Tactic for controlling motor symptoms of advanced Parkinson's disease

January 25, 2018
Standard drug treatment for Parkinson's disease can over time induce motor complications that reduce the effectiveness of restoring mobility. These complications include abnormal involuntary movements known as dyskinesias. ...

A new therapeutic avenue for Parkinson's disease

January 23, 2018
Systemic clearing of senescent astrocytes prevents Parkinson's neuropathology and associated symptoms in a mouse model of sporadic disease, the type implicated in 95% of human cases. Publishing in Cell Reports, researchers ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.