Researchers create novel probiotic beer that boosts immunity and improves gut health

June 28, 2017, National University of Singapore
Associate Professor Liu Shao Quan (left) and Miss Chan Mei Zhi Alcine (right) from the Food Science and Technology Programme at NUS created a novel probiotic beer that boosts immunity and improves gut health. Credit: National University of Singapore

Beer lovers may soon have a gut-friendly drink to raise a toast to, thanks to the creation of a novel probiotic sour beer by a team of researchers from the National University of Singapore (NUS). This new specialty beer incorporates the probiotic strain Lactobacillus paracasei L26, which was first isolated from human intestines and has the ability to neutralise toxins and viruses, as well as regulate the immune system.

The idea of producing a probiotic was first mooted by Miss Chan Mei Zhi Alcine, a fourth-year student from the Food Science and Technology Programme under the NUS Faculty of Science, who consumes dairy-based probiotic beverages daily.

"The of are well known. While good bacteria are often present in food that have been fermented, there are currently no beers in the market that contain probiotics. Developing sufficient counts of live probiotics in beer is a challenging feat as beers contain hop acids that prevent the growth and survival of probiotics. As a believer of achieving a healthy diet through consuming probiotics, this is a natural choice for me when I picked a topic for my final-year project," said Miss Chan, who will be graduating with a Bachelor of Applied Science with Honours (Highest Distinction) from NUS in July 2017.

Infusing beer with health benefits

Studies have shown that consuming food and beverages with live counts of probiotics are more effective in delivering health effects than eating those with inactive probiotics. Currently, the recommendation by the International Scientific Association for Probiotics and Prebiotics is to have a minimum of 1 billion probiotics per serving in order to attain the maximum health benefits.

Under the supervision of Associate Professor Liu Shao Quan from the NUS Food Science and Technology Programme, Miss Chan took about nine months to come up with an ideal recipe that achieves the optimal count of live probiotics in the beer.

By propagating the probiotic and yeast in pure cultures, and modifying conventional brewing and fermentation processes, Miss Chan managed to increase and maintain the live counts of the strain of probiotic. "For this beer, we used a lactic acid bacterium as a probiotic micro-organism. It will utilise sugars present in the wort to produce sour-tasting lactic acid, resulting in a beer with sharp and tart flavours. The final product, which takes around a month to brew, has an alcohol content of about 3.5 per cent," explained Miss Chan. The NUS research team has filed a patent to protect the recipe for brewing the probiotic sour beer.

Assoc Prof Liu said, "The general health benefits associated with consuming food and beverages with probiotic strains have driven demand dramatically. In recent years, consumption of craft or specialty beers has gained popularity too. Alcine's invention is placed in a unique position that caters to these two trends. I am confident that the probiotic gut-friendly beer will be well-received by beer drinkers, as they can now enjoy their beers and be healthy."

Looking ahead, Assoc Prof Liu and Miss Chan are keen to collaborate with industry partners to introduce the beer to consumers.

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