Rivaroxaban OK for stroke prevention in cancer patients

Rivaroxaban OK for stroke prevention in cancer patients

(HealthDay)—The safety and efficacy of rivaroxaban treatment for nonvalvular atrial fibrillation (AF) in patients with active cancer is similar to the general population, according to a study published in the July 15 issue of the American Journal of Cardiology.

Eva S. Laube, M.D., from the Memorial Sloan Kettering Cancer Center in New York City, and colleagues assessed the safety and efficacy of rivaroxaban in 163 patients with active cancer and AF treated from Jan. 1, 2014, to March 31, 2016. Outcomes were assessed from medical records.

After adjusting for competing risks, the researchers found that the estimated one-year cumulative incidence of was 1.4 percent and major bleeding was 1.2 percent. At one year, the risk of clinically relevant nonmajor bleeding leading to discontinuation of anticoagulation was 14.0 percent, while the cumulative incidence of mortality was 22.6 percent, reflecting an active cancer population. There was one death following an acute ischemic cerebrovascular insult.

"The safety and efficacy of rivaroxaban treatment for nonvalvular AF in patients with active is comparable to the results of the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET-AF) study in the ," the authors write.

More information: Abstract
Full Text (subscription or payment may be required)

Journal information: American Journal of Cardiology

Copyright © 2017 HealthDay. All rights reserved.

Citation: Rivaroxaban OK for stroke prevention in cancer patients (2017, July 13) retrieved 25 July 2024 from https://medicalxpress.com/news/2017-07-rivaroxaban-cancer-patients.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

Lower risk of gastrointestinal bleeding for apixaban

0 shares

Feedback to editors