Rod, cone function down for children born extremely preterm

Rod, cone function down for children born extremely preterm

(HealthDay)—Children born extremely preterm have reduced rod and cone function compared with children born at term, according to a study published online June 29 in JAMA Ophthalmology.

Anna E.C. Molnar, M.D., Ph.D., from Uppsala University in Sweden, and colleagues compared in 6.5-year-old born extremely preterm (52 children) and children born at term (45 children). Retinal function was assessed using full-field electroretinographic (ffERG) recordings.

The researchers found that, compared with the born at term, the preterm group had significantly lower amplitudes of the combined rod and cone responses (a-wave of the dark-adapted electroretinographic [ERG] protocol of 3.0 and 12.0 candelas [cd]/s/m²: mean differences, −48.9 and −55.7 µV, respectively) and of the isolated cone (30-Hz Flicker ERG: mean difference, −12.1 µV). The preterm group also had longer implicit time of the combined rod and cone responses (a-wave of the dark-adapted ERG protocol of 12.0 cd/s/m²: mean difference, 1.2 ms) and isolated cone responses (30-Hz flicker ERG: mean difference, 1.2 ms), compared with the group born at term. In the preterm group there was no correlation between ffERG recordings and gestational age or retinopathy of prematurity.

"There was no association with retinopathy of prematurity in the preterm group, which suggests that being born extremely preterm may be one of the main reasons for a general retinal dysfunction," the authors write.


Explore further

Insulin sensitivity lower in adults born preterm

More information: Abstract/Full Text
Editorial (subscription or payment may be required)
Journal information: JAMA Ophthalmology

Copyright © 2017 HealthDay. All rights reserved.

Citation: Rod, cone function down for children born extremely preterm (2017, July 7) retrieved 25 May 2022 from https://medicalxpress.com/news/2017-07-rod-cone-function-children-born.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
2 shares

Feedback to editors