What's the best strategy to increase living kidney donation?

August 17, 2017

A new analysis indicates that few strategies to increase living kidney donation have been evaluated effectively; however, educational strategies targeted to recipients and their family and friends have the best evidence of being successful. The analysis, which appears in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN), also provides possible suggestions that could help investigators, organizations, and policy makers determine which, out of the many strategies that may be used to increase living donation, should be considered.

There is a critical need to increase rates of living kidney donation to address the growing organ shortage; however, it's unclear which strategies are effective. To investigate, Scott Klarenbach, MD, MSc (University of Alberta) and his colleagues summarized the breadth and quality of the evidence on approaches to increase living kidney donation.

When the researchers conducted a search of the medical literature, they found very few high quality studies. The most evidence related to educational strategies: those directed at both the potential recipient and their close social network. Of the 7 studies that focused on educational strategies, 2 studies that targeted the potential recipient's close social network reported significant benefits. Other approaches were also identified, but their impact was assessed through less rigorous study designs.

"Living kidney donation is the optimal treatment for patients with , who would otherwise be treated with dialysis. It improves survival and quality of life, and is less resource intensive and can be safely performed with appropriate donor selection," said Dr. Klarenbach. "There are large numbers of patients with kidney failure waiting for a kidney transplant, and increasing living would reduce their wait time and improve outcomes."

In an accompanying editorial, Krista Lentine, MD, PhD (Saint Louse University School of Medicine) Didier Mandelbrot, MD (University of Wisconsin School of Medicine) noted that certain steps are needed for practitioners and policymakers to expand living donor kidney transplantation. "We and others believe that the strategies that have the potential to improve informed consent and access to living kidney donor transplantation include: (a) broader and repeated living donor transplantation education beginning at earlier stages of and involving the patient's social network, (b) removal of disincentives to donation, (c) optimized efficiency in the evaluation of donor candidates, and (d) improving the safety and defensibility of selection," they wrote.

Explore further: Calculator estimates success of kidney transplants with particular donor-recipient pairs

More information: "A Scoping Review for Strategies to Increase Living Kidney Donation," Clinical Journal of the American Society of Nephrology (2017). DOI: 10.2215/CJN.01470217

Related Stories

Calculator estimates success of kidney transplants with particular donor-recipient pairs

June 8, 2017
Researchers have developed a calculator that estimates the likelihood that a given patient who receives a kidney transplant from a particular living donor would have a functioning kidney 5 and 10 years after transplantation. ...

Socioeconomic status a significant barrier to living kidney donation for African Americans

August 29, 2013
Socioeconomic status is a more important barrier to living kidney donation than cultural factors, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The findings ...

Program may help increase numbers of live kidney donors

November 17, 2016
A new program may help overcome common barriers to finding living kidney donors. The program will be highlighted at ASN Kidney Week 2016 November 15-20 at McCormick Place in Chicago, IL.

Study quantifies kidney failure risk in living kidney donors

April 27, 2017
Researchers have developed a risk calculator to provide personalized risk estimates of developing kidney failure after donation. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology ...

HIV+ kidney failure patients face hurdles in receiving necessary transplants

February 23, 2017
A new study finds that HIV-infected individuals with kidney failure are less likely to receive a kidney transplant—especially from living donors—than their uninfected counterparts. The study appears in an upcoming issue ...

Gender disparities uncovered in desire to receive living donor kidney transplants

August 14, 2014
Among black kidney failure patients undergoing dialysis, women are much less likely than men to want to receive kidney transplants from living donors, despite more offers from family and friends. The findings, which are from ...

Recommended for you

Female researchers pay more attention to sex and gender in medicine

November 7, 2017
When women participate in a medical research paper, that research is more likely to take into account the differences between the way men and women react to diseases and treatments, according to a new study by Stanford researchers.

Drug therapy from lethal bacteria could reduce kidney transplant rejection

August 3, 2017
An experimental treatment derived from a potentially deadly microorganism may provide lifesaving help for kidney transplant patients, according to an international study led by investigators at Cedars-Sinai.

Exploring the potential of human echolocation

June 25, 2017
People who are visually impaired will often use a cane to feel out their surroundings. With training and practice, people can learn to use the pitch, loudness and timbre of echoes from the cane or other sounds to navigate ...

Team eradicates hepatitis C in 10 patients following lifesaving transplants from infected donors

April 30, 2017
Ten patients at Penn Medicine have been cured of the Hepatitis C virus (HCV) following lifesaving kidney transplants from deceased donors who were infected with the disease. The findings point to new strategies for increasing ...

'bench to bedside to bench': Scientists call for closer basic-clinical collaborations

March 24, 2017
In the era of genome sequencing, it's time to update the old "bench-to-bedside" shorthand for how basic research discoveries inform clinical practice, researchers from The Jackson Laboratory (JAX), National Human Genome Research ...

The ethics of tracking athletes' biometric data

January 18, 2017
(Medical Xpress)—Whether it is a FitBit or a heart rate monitor, biometric technologies have become household devices. Professional sports leagues use some of the most technologically advanced biodata tracking systems to ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.