Acetaminophen may help reduce postoperative shivering

Administering acetaminophen, such as Tylenol, during surgery may reduce the incidence of postoperative shivering, suggests a study being presented at the ANESTHESIOLOG 2017 annual meeting.

Chills and shivering are a common side effect that happens when patients regain consciousness after . Shivering can occur in up to half of patients. While the exact cause is unknown, scientists believe it may be related to the body cooling down.

"Postoperative shivering is a frequent complication in patients recovering from general anesthesia. It causes significant pain and discomfort," said lead researcher Takahiro Tadokoro, M.D., a physician anesthesiologist at the University of the Ryukyus in Okinawa, Japan. "Postoperative shivering can also put a strain on the cardiovascular system, therefore we need to prevent it, especially in patients with cardiopulmonary risk."

Acetaminophen is being used more and more pre- and postoperatively in an effort to control pain and to minimize opioids, Dr. Tadokoro noted. Until now, few studies have evaluated the ability of to prevent postoperative shivering.

The study included 37 patients scheduled for gynecologic surgery. Patients were randomly assigned to receive acetaminophen (15 mg per kilogram of body weight) intravenously, or a , after receiving . Among the women who received acetaminophen, 22.2 percent experienced postoperative shivering, compared to 73.7 percent of those who received the placebo.

Additionally, the severity of shivering was significantly lower among women who received acetaminophen. Body temperature was significantly lower 30 minutes after researchers began their observation in the recovery room among patients who received acetaminophen compared to those who received the placebo.

"We believe our findings can be widely applicable, as acetaminophen is a relatively safe drug and commonly used," Dr. Tadokoro said.


Explore further

IV acetaminophen eases post-spinal op pain for children

Provided by American Society of Anesthesiologists
Citation: Acetaminophen may help reduce postoperative shivering (2017, October 22) retrieved 17 August 2019 from https://medicalxpress.com/news/2017-10-acetaminophen-postoperative.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
0 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more