Bone strength + bone mineral density screening cost-effective

October 29, 2017

(HealthDay)—Combined assessment of bone strength and bone mineral density is a cost-effective strategy for osteoporosis screening in postmenopausal women, according to a study published in the November issue of Radiology.

Christoph A. Agten, M.D., from the NYU Langone Medical Center in New York City, and colleagues created a model to investigate whether assessment of bone strength with quantitative computed tomography (CT) in combination with dual-energy x-ray absorptiometry (DXA) is cost-effective as a screening tool for osteoporosis in (≥55 years).

The researchers found that the most cost-effective strategy was combined DXA and quantitative CT screening starting at age 55 with quantitative CT screening every five years (incremental cost-effectiveness ratio, $2,000 per quality-adjusted life year). With this strategy, 12.8 percent of postmenopausal women sustained hip fractures in their remaining life versus 18.7 percent with no screening and 15.8 percent with DXA screening. Vertebral fractures would happen in 7.5, 11.1, and 9 percent, respectively, while wrist fractures were predicted in 14, 17.8, and 16.4 percent, respectively. DXA and quantitative CT at age 55 years with quantitative CT screening every five years was the best strategy in more than 90 percent of the 1,000 simulations.

"Combined assessment of and is a cost-effective strategy for osteoporosis screening in postmenopausal women and has the potential to prevent a substantial number of fragility fractures," the authors write.

Explore further: Blood marker may predict postmenopausal women's risk of bone fractures

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Blood marker may predict postmenopausal women's risk of bone fractures

August 16, 2017
In a study published in the Journal of Bone and Mineral Research, blood tests that detect fragments of a protein secreted by bone cells helped to predict fracture risk in postmenopausal women, independently of bone mineral ...

ASBMR: Romosozumab reduces fracture rate in osteoporosis

September 12, 2017
(HealthDay)—Romosozumab treatment followed by alendronate is linked to reduced risk of fractures versus alendronate alone for postmenopausal women with osteoporosis, according to a study published online Sept. 11 in the ...

Abaloparatide benefits a wide range of postmenopausal women with osteoporosis

September 19, 2016
A recent analysis of results from a randomized controlled clinical trial indicates that abaloparatide-SC, a novel therapy for osteoporosis, provides consistent protection against bone fractures in postmenopausal women with ...

Osteoporosis screening and treatment fall short for women with hip fractures

February 23, 2017
It's important to identify and treat osteoporosis following hip fracture, but a large study found low rates of assessment and treatment in postmenopausal women who had suffered a hip fracture.

Osteoporosis screening guidelines miss many younger post-menopausal women

October 21, 2014
To reduce the risk of bone fractures and the complications arising from them, the United States Preventive Services Task force (USPSTF) recommends that all women age 65 and older be tested and treated for low bone mineral ...

Assessment of bone density and fracture history can predict long-term fracture risk

June 21, 2017
Factors such as low bone density and previous fractures are commonly used to predict an individual's risk of experiencing a fracture over the next 10 years. A new analysis has found that a single bone density measurement ...

Recommended for you

Pre-clinical success for a universal flu vaccine offers hope for third generation approach

September 21, 2018
Researchers from the University of Oxford's Department of Zoology have demonstrated pre-clinical success for a universal flu vaccine in a new paper published in Nature Communications.

Fighting a deadly parasite: Scientists devise a method to store Cryptosporidium, aiding vaccine research efforts

September 21, 2018
In May, just before one of the hottest summers on record, the U.S. Centers for Disease Control and Prevention issued a warning about diseases lurking in recreational water facilities like swimming pools and water playgrounds. ...

Scientists make significant discovery in the fight against drug-resistant tuberculosis

September 20, 2018
A team of scientists have identified a naturally occurring antibiotic that may help in the fight against drug-resistant Tuberculosis.

Anti-cancer drugs may hold key to overcoming antimalarial drug resistance

September 20, 2018
Scientists have found a way to boost the efficacy of the world's most powerful antimalarial drug with the help of chemotherapy medicines, according to new research published in the journal Nature Communications.

Affordable Care Act: Study finds surprising gaps in HIV care providers' knowledge

September 20, 2018
A new study has revealed surprising gaps in some HIV medical providers' knowledge of the Affordable Care Act, with more than a quarter of providers surveyed unable to say whether their state had expanded Medicaid.

Preventing a dengue outbreak at the 2020 Summer Olympics

September 20, 2018
In 2014, a dengue outbreak unexpectedly occurred in Tokyo. What does that mean for the 2020 summer Olympics and Paralympics being held in the city? Researchers report this week in PLOS Neglected Tropical Diseases that new ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.