Distinct features for drug use-related endophthalmitis

November 20, 2017

(HealthDay)—Patients with injection drug use (IDU) endogenous endophthalmitis (EE) are younger, with fewer comorbidities, and have more improvement in visual acuity after intervention compared with non-IDU EE patients, according to a research letter published online Nov. 16 in JAMA Ophthalmology.

Preston M. Luong, from Geisel School of Medicine at Dartmouth in Hanover, New Hampshire, and colleagues conducted a retrospective medical record review identifying EE cases from Jan. 1, 2012, through Dec. 5, 2016, to examine the clinical characteristics of IDU versus non-IDU EE.

The researchers identified 15 with EE (five males and 10 females), of whom nine had a history of IDU. The number of non-IDU EE cases remained at zero to two per year during the study period, while the number of IDU EE cases varied from zero to four per year; the most cases occurred in 2016. The most common presenting symptom was reduced vision, which was seen for all nine patients with IDU EE and five of the six patients with non-IDU EE. Patients with IDU were younger, had fewer comorbidities, and tended to delay seeking medical care. In addition, they had more negative intraocular and blood culture findings for EE, and they experienced significantly more improvement in after intervention.

"The patients with IDU represent a younger and healthier subset of the population with EE and may regain vision with prompt recognition and treatment," the authors write.

Explore further: Cases of low vision, blindness estimated to double in 30 years

More information: Abstract/Full Text (subscription or payment may be required)

Related Stories

Cases of low vision, blindness estimated to double in 30 years

November 3, 2017
(HealthDay)—Prevalence and incidence rates of low vision and blindness demonstrate a growing need for low vision rehabilitation services in the United States, according to a study published online Nov. 2 in JAMA Ophthalmology.

Facility volume found to impact nasopharyngeal CA survival

November 6, 2017
(HealthDay)—Treatment at a high-volume facility (HVF) is a significant predictor of improved overall survival in nasopharyngeal cancer (NPC), according to a research letter published online Nov. 2 in JAMA Otolaryngology—Head ...

Self-care tools cut depression in AMD, diabetic retinopathy

December 14, 2016
(HealthDay)—Self-care tools can reduce depressive symptoms in patients with age-related macular degeneration (AMD) or diabetic retinopathy (DR), according to a study published online Dec. 7 in Clinical & Experimental Ophthalmology.

Rise in endogenous Klebsiella pneumoniae endophthalmitis

September 2, 2016
(HealthDay)—Increasing trends of endogenous Klebsiella pneumoniae endophthalmitis (EKPE) have been reported in Australia, according to research published online Aug. 26 in Clinical & Experimental Ophthalmology.

Amblyopia Tx at young age results in good vision later

July 16, 2014
(HealthDay)—Most children treated for moderate amblyopia when younger than 7 years have good visual acuity at 15 years of age, according to a study published in the July issue of JAMA Ophthalmology.

Wound leak critical complication post open globe repair

March 4, 2015
(HealthDay)—Postoperative wound leak affects a substantial proportion of eyes following repair of open globe injuries, according to a study published online Feb. 17 in Clinical & Experimental Ophthalmology.

Recommended for you

Drinking hot tea every day linked to lower glaucoma risk

December 14, 2017
Drinking a cup of hot tea at least once a day may be linked to a significantly lower risk of developing the serious eye condition, glaucoma, finds a small study published online in the British Journal of Ophthalmology.

Newly published research provides new insight into how diabetes leads to retinopathy

December 7, 2017
An international team of scientists led by Professor Ingrid Fleming of Goethe University, Frankfurt, Germany, and including Professor Bruce Hammock of the University of California, Davis, provides new insight into the mechanism ...

Researchers use breakthrough technology to understand eclipse eye damage

December 7, 2017
In a first-of-its-kind study, Mount Sinai researchers are using adaptive optics (AO) to analyze retinal eye damage from the August solar eclipse on a cellular level. The research could help doctors develop a deeper understanding ...

Combating eye injuries with a reversible superglue seal

December 6, 2017
When a soldier sustains a traumatic eye injury on the battlefield, any delay in treatment may lead to permanent vision loss. With medical facilities potentially far away and no existing tools to prevent deterioration, medics ...

Trigger for most common form of vision loss discovered

November 27, 2017
In a major step forward in the battle against macular degeneration, the leading cause of vision loss among the elderly, researchers at the University of Virginia School of Medicine have discovered a critical trigger for the ...

Scientists engineer drug delivery device that treats glaucoma directly inside the eye

November 23, 2017
Glaucoma, which affects over 60 million people worldwide, can seem easy to treat: medicated eye drops can be used to ease the buildup of fluid in the eye that underlies the condition. If glaucoma is caught early, eye drops ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.