Distinct features for drug use-related endophthalmitis

November 20, 2017

(HealthDay)—Patients with injection drug use (IDU) endogenous endophthalmitis (EE) are younger, with fewer comorbidities, and have more improvement in visual acuity after intervention compared with non-IDU EE patients, according to a research letter published online Nov. 16 in JAMA Ophthalmology.

Preston M. Luong, from Geisel School of Medicine at Dartmouth in Hanover, New Hampshire, and colleagues conducted a retrospective medical record review identifying EE cases from Jan. 1, 2012, through Dec. 5, 2016, to examine the clinical characteristics of IDU versus non-IDU EE.

The researchers identified 15 with EE (five males and 10 females), of whom nine had a history of IDU. The number of non-IDU EE cases remained at zero to two per year during the study period, while the number of IDU EE cases varied from zero to four per year; the most cases occurred in 2016. The most common presenting symptom was reduced vision, which was seen for all nine patients with IDU EE and five of the six patients with non-IDU EE. Patients with IDU were younger, had fewer comorbidities, and tended to delay seeking medical care. In addition, they had more negative intraocular and blood culture findings for EE, and they experienced significantly more improvement in after intervention.

"The patients with IDU represent a younger and healthier subset of the population with EE and may regain vision with prompt recognition and treatment," the authors write.

Explore further: Cases of low vision, blindness estimated to double in 30 years

More information: Abstract/Full Text (subscription or payment may be required)

Related Stories

Cases of low vision, blindness estimated to double in 30 years

November 3, 2017
(HealthDay)—Prevalence and incidence rates of low vision and blindness demonstrate a growing need for low vision rehabilitation services in the United States, according to a study published online Nov. 2 in JAMA Ophthalmology.

Facility volume found to impact nasopharyngeal CA survival

November 6, 2017
(HealthDay)—Treatment at a high-volume facility (HVF) is a significant predictor of improved overall survival in nasopharyngeal cancer (NPC), according to a research letter published online Nov. 2 in JAMA Otolaryngology—Head ...

Self-care tools cut depression in AMD, diabetic retinopathy

December 14, 2016
(HealthDay)—Self-care tools can reduce depressive symptoms in patients with age-related macular degeneration (AMD) or diabetic retinopathy (DR), according to a study published online Dec. 7 in Clinical & Experimental Ophthalmology.

Rise in endogenous Klebsiella pneumoniae endophthalmitis

September 2, 2016
(HealthDay)—Increasing trends of endogenous Klebsiella pneumoniae endophthalmitis (EKPE) have been reported in Australia, according to research published online Aug. 26 in Clinical & Experimental Ophthalmology.

Amblyopia Tx at young age results in good vision later

July 16, 2014
(HealthDay)—Most children treated for moderate amblyopia when younger than 7 years have good visual acuity at 15 years of age, according to a study published in the July issue of JAMA Ophthalmology.

Wound leak critical complication post open globe repair

March 4, 2015
(HealthDay)—Postoperative wound leak affects a substantial proportion of eyes following repair of open globe injuries, according to a study published online Feb. 17 in Clinical & Experimental Ophthalmology.

Recommended for you

An orange a day keeps macular degeneration away: 15-year study

July 12, 2018
A new study has shown that people who regularly eat oranges are less likely to develop macular degeneration than people who do not eat oranges.

Injectable electronics offer powerful new tool in understanding how retinal cells work

June 28, 2018
Charles Lieber and his group are rewriting the rules of how scientists study retinal cells, and they're doing it with a single injection.

Why the eye could be the window to brain degeneration such as Alzheimer's disease

June 26, 2018
Researchers from Queen's University Belfast have shown for the first time that the eye could be a surrogate for brain degeneration like Alzheimer's disease (AD).

Microglia protect sensory cells needed for vision after retinal detachment

June 18, 2018
A research team at Massachusetts Eye and Ear has shown that microglia, the primary immune cells of the brain and retina, play a protective role in response to retinal detachment. Retinal detachment and subsequent degeneration ...

161 genetic factors for myopia identified

June 15, 2018
The international Consortium for Refractive Error and Myopia (CREAM) recently published the largest-ever genetic study of myopia in Nature Genetics. Researchers from the Gutenberg Health Study at the Medical Center of Johannes ...

Normal eye dominance is not necessary for restoring visual acuity in amblyopia

June 7, 2018
Amblyopia, commonly known as "lazy eye," is a visual disorder common in children. The symptoms often are low acuity in the affected or "lazy" eye and impaired depth perception. Researchers have long believed that the impaired ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.